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Skip to Search Results- 1Abu Alrub, Osama Y
- 1Agellon, Luis B.
- 1Chow, Ava Kalyca
- 1Clark, A.M.
- 1Fliegel, Larry
- 1Gamble, James.
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Fall 2012
The heart requires an uninterrupted supply of fuels to sustain its physiological function. Fatty acids are the predominant substrates and endogenous triglyceride turnover contributes significantly to fatty acid oxidation. Lipins are cytosolic, bifunctional enzymes involved in both glycerolipid...
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Fall 2014
Cardiac Fatty acids β-oxidation (FAO) markedly increases during maturation and become the major source of energy for the adult heart. However, excessive rates of FAO can compromise cardiac function in obesity, diabetes, and heart failure. Lysine acetylation has recently been identified as a...
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2002
Clark, A.M., MacIntyre, P.D., Sharp, C.
Access to health care should be determined by clinical need and not by age. Older people form an increasing proportion of the general population and of those with coronary heart disease, but compared with younger people they are less likely to be invited for cardiac rehabilitation programmes and...
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Spring 2011
The traditional PI3K pathway relies on agonist mediated stimulation of PI3Kα through RTKs and PI3Kγ through GPCRs, which stimulate downstream enzymes such as Akt. This pathway has been found to be important in cardiomyocytes and cardiofibroblasts for regulating cardiac morphology and function....
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Fall 2012
Heart disease is a leading cause of morbidity and mortality in the world with a growing prevalence in a variety of manifestations. Many of the events that occur in the heart during the progression of disease have been explored to identify a causative mechanism to develop effective treatments and...
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Fall 2023
Thump Thump. Swoosh, swoosh. Kamlamunikk. Heart. Mi’kmaq teachings of heart are tied to concepts such as moontime, spirits, ancestors and blood knowledge. Being a Mi’kmaq woman from the west coast of Newfoundland with strong lifelong community connection I was aware that the understanding of...