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Spring 2020
Cardiovascular disease (CVD) is the leading cause of morbidity and mortality worldwide, while ischemic heart disease (IHD) dominates the cause of CVD mortality. Following myocardial infarction (MI), the heart experiences a series of structural and functional changes, termed post-infarction...
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Spring 2011
The traditional PI3K pathway relies on agonist mediated stimulation of PI3Kα through RTKs and PI3Kγ through GPCRs, which stimulate downstream enzymes such as Akt. This pathway has been found to be important in cardiomyocytes and cardiofibroblasts for regulating cardiac morphology and function....
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