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Skip to Search Results- 25Graduate and Postdoctoral Studies (GPS), Faculty of
- 25Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 16Chemistry, Department of
- 16Chemistry, Department of/Journal Articles (Chemistry)
- 13Biological Sciences, Department of
- 13Biological Sciences, Department of/Journal Articles (Biological Sciences)
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Structural variant detection by large-scale sequencing reveals new evolutionary evidence on breed divergence between Chinese and European pigs
Download2016
Liu, Jian-Feng, Fan, Ziyao, Li, Junhui, Wang, Jiafu, Wang, Zhiquan, Zhao, Pengju, Kang, Huimin, Zhang, Qin, Yin, Zongjun, Wang, Haifei
In this study, we performed a genome-wide SV detection among the genomes of thirteen pigs from diverse Chinese and European originated breeds by next genetation sequencing, and constrcuted a single-nucleotide resolution map involving 56,930 putative SVs. We firstly identified a SV hotspot...
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2016-01-01
Song, Qiao, Gao, Yongfeng, Xu, Jiang-Fei, Qin, Bo, Serpe, Michael J., Zhang, Xi
This letter describes a new method for fabricating supramolecular microgels from supramonomers. To this end, we designed and assembled supramonomers with one acrylate moiety on each end on the basis of noncovalent host–guest interactions, which could be utilized as a cross-linker. Then...
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Targeted delivery of mycobacterial antigens to human dendritic cells via Siglec-7 induces robust T cell activation
2014
Macauley, M. S., Cheng, T. Y., Moody, D. B., Paulson, J. C. , Kawasaki, N., Van Rhijn, I., Rillahan, C. D.
Lipids from mycobacteria can be presented to human T cells by group 1 CD1 Ag-presenting molecules (CD1a, CD1b, and CD1c). Group 1 CD1-restricted T cells are activated by lipid Ags presented by myeloid dendritic cells (DCs), after which they generate antibacterial effector functions, including...
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Fall 2014
The assembly of nanoparticle building blocks into more complex nanostructures has important applications in analytical chemistry, materials science, medical science, optics, and electronics. Due to its exquisite specificity and programmable nature, DNA has emerged as a very promising biomolecule...
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The Influence of Specific Ions and System Architecture on the Recognition and Reactivity of Two Charged Materials: DNA-Modified Gold Nanoparticle Aggregates and Planar Silica
DownloadFall 2014
DNA functionalized gold nanoparticles (GNP–DNA) offer simple colorimetric nucleic acid sensing with high selectivity and sensitivity. Consequently, they are promising in genetic profiling, disease diagnostics, and forensic applications. In the presence of a target nucleic acid, GNP–DNA forms...
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The isolation and characterization of two Stenotrophomonas maltophilia bacteriophages capable of cross-taxonomic order infectivity
Download2015
Lynch, Karlene H.Stothard, Paul, Peters, Danielle L., Dennis, Jonathan J.
Background A rapid worldwide increase in the number of human infections caused by the extremely antibiotic resistant bacterium Stenotrophomonas maltophilia is prompting alarm. One potential treatment solution to the current antibiotic resistance dilemma is “phage therapy”, the clinical...
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Fall 2020
The term “recognition” is a commonly employed category in the political scene. Colloquially, it designates a moral demand on part of the bearers of injustice to be treated with dignity and respect. But recognition is not merely a demand, but also an action; it has addressors, but also addressees,...
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The mitochondrial genome of the hexactinellid sponge Aphrocallistes vastus: Evidence for programmed translational frameshifting
Download2008
Rosengarten, R.D., Sperling, E.A., Leys, S.P., Dellaporta, S.L., Moreno, M.A.
Background: Mitochondrial genomes (mtDNA) of numerous sponges have been sequenced as part of an ongoing effort to resolve the class-level phylogeny of the Porifera, as well as to place the various lower metazoan groups on the animal-kingdom tree. Most recently, the partial mtDNA of two glass...
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Spring 2024
DNA double-strand breaks (DSBs) are considered the most deleterious DNA lesions. Unrepaired or incorrectly repaired DSBs can lead to cell cycle arrest, apoptosis, or over time, the accumulation of mutations and chromosomal abnormalities that give rise to cancer. The repair of DSBs by homologous...