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Skip to Search Results- 4Anesthesia
- 3Adiposity
- 3Electrophysiology
- 2Sleep
- 12-p-(2-carboxyethyl)-phenethylamino-5′-N-ethylcarboxamidoadenosine-hydrochloride
- 1Adenosine
- 1Darvesh, Nazia
- 1Ebadi, Maryam
- 1Gragasin, Ferrante S.
- 1Pravdivyi, Igor
- 1Singh, Aakanksha
- 1Toossi, Amirali
- 1Clayton T. Dickson (Psychology, Physiology, Anesthesia and Pain Medicine, Neuroscience and Mental Health Institute)
- 1Davidge, Sandra (dept. of Physiology)
- 1Dickson, Clayton (Neuroscience and Mental Health Institute, Psychology, Physiology, Anesthesiology and Pain Medicine
- 1Maximova, Katerina (Public Health Sciences)
- 1Mazurak, Vera (Agricultural, Food & Nutritional Science)
- 1Mushahwar, Vivian (Medicine)
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Fall 2022
The reason and functional relevance of why we sleep continues to perplex researchers. One fundamental reason behind why sleep remains a mystery is because it is challenging to study given how easily it is disrupted. Anesthesia has been suggested to be a model for studying sleep given the...
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Adiposity and fat loss in cancer: Exploring the prognostic significance and underlying mechanisms of adipose alterations in cancer
DownloadSpring 2017
During cancer progression, many patients will experience some degree of wasting of both muscle and adipose tissue. However, little is-known about adipose tissue alterations after a cancer diagnosis. Therefore, this research was conducted to first understand the prognostic significance of adipose...
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Anesthesia and the Aging Vasculature: Effects of Propofol on Hemodynamics and Vascular Function
DownloadSpring 2014
An increasing life expectancy in Canada has resulted in increasing proportions of elderly patients requiring anesthetic care for surgical procedures. Aging is associated with cardiovascular changes resulting in increased vasoconstriction and hypertension, and medications such as angiotensin...
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Fall 2014
An individual’s body weight is tightly regulated by balancing food intake with energy expenditure. This is accomplished in part by secretion of the hormone leptin by adipocytes, an excess of which signals to reduce appetite and increase activity through action in the hypothalamic region of the...
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Fall 2023
Sleep is a vital neurobiological process, yet despite its fundamental significance, delineating the endogenous neural pathways involved has been slow to progress due to a lack of diverse sleep models. Anesthesia, which has direct behavioural parallels to natural sleep, and which is often linked...
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Spring 2014
Modifiable cardiovascular disease (CVD) risk factors, such as adiposity, are already associated with atherosclerotic progression in childhood. Less is known about whether physical activity (PA) is associated with progression of atherosclerosis in non-clinical samples of children. This...
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Towards Clinical Testing of Intraspinal Microstimulation for Restoration of Walking after Spinal Cord Injury
DownloadSpring 2019
The overall goal of this thesis was to advance intraspinal microstimulation (ISMS) towards clinical testing for the purpose of restoring walking after spinal cord injury. ISMS implants focus on restoring mobility after spinal cord injury by activating the intact spinal motor networks below the...