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Skip to Search Results- 10Klassen, John S.
- 10Young, T. Kue
- 6Kitova, Elena N.
- 5Proctor, Spencer D.
- 4Liu, Lan
- 4Lowary, Todd L.
- 47Graduate and Postdoctoral Studies (GPS), Faculty of
- 47Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 14Agricultural, Food and Nutritional Science, Department of
- 14Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
- 10Chemistry, Department of
- 10Chemistry, Department of/Journal Articles (Chemistry)
- 10Department of Agricultural, Food, and Nutritional Science
- 7Department of Surgery
- 4Department of Chemistry
- 4Faculty of Pharmacy and Pharmaceutical Sciences
- 4School of Public Health
- 2Department of Medical Microbiology and Immunology
- 2Johnson, Jeff A. (School of Public Health Sciences, University of Alberta)
- 2Proctor, Spencer (AFNS)
- 2Williams, Beverly (Faculty of Nursing, University of Alberta)
- 1Al Hamarneh, Yazid (Pharmacology)
- 1Anderson, Colin (Medical Microbiology and Immunology and Surgery)
- 1Baldwin, Troy (Medical Microbiology and Immunology)
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Identifying carbohydrate ligands of a norovirus P particle using a catch and release electrospray ionization mass spectrometry assay
Download2014
Jiang, Xi, Kitova, Elena N., Klassen, John S., Tan, Ming, Han, Ling
Noroviruses (NoVs), the major cause of epidemic acute gastroenteritis, recognize human histo-blood group antigens (HBGAs), which are present as free oligosaccharides in bodily fluid or glycolipids and glycoproteins on the surfaces of cells. The subviral P particle formed by the protruding (P)...
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Impaired de novo choline synthesis explains why phosphatidylethanolamine N-methyltransferase-deficient mice are protected from diet-induced obesity
Download2010
Kuo, Ming-Shang, Dyck, Jason R. B., Sletten, Torunn, Proctor, Spencer D., Jacobs, René L., Lingrell, Susanne, Cao, Guoqing, Peake, David A., Kennedy, Brian P., Zhao, Yang, Vance, Dennis E., Koonen, Debby P. Y., Su, Brian
Phosphatidylcholine (PC) is synthesized from choline via the CDP-choline pathway. Liver cells can also synthesize PC via the sequential methylation of phosphatidylethanolamine, catalyzed by phosphatidylethanolamine N-methyltransferase (PEMT). The current study investigates whether or not hepatic...
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Insulin and testosterone are associated with elevated intestinal secretion of lipids and lipoproteins in a rodent model of the metabolic and polycystic ovary syndrome
Download2014
Wang, Ye, Shi, Danni, Proctor, Spencer D., Vine, Donna F.
The metabolic syndrome is highly associated with the incidence of Polycystic Ovary Syndrome (PCOS). The metabolic aberrations of insulin resistance and hyperandrogenemia have been proposed to contribute to the development of dyslipidemia and increased Cardiovascular Disease (CVD) risk in PCOS....
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International Comparison of Time to Treatment Intensification and Rates of Complications in Metformin Monotherapy Treated Type 2 Diabetes Patients
DownloadFall 2018
Type 2 diabetes mellitus is a progressive disease which affects many people in Canada and the United States, and the prevalence of type 2 diabetes is only expected to increase in the future. Pharmacological interventions are a cornerstone of the management of type 2 diabetes as they help to...
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Fall 2020
2-aminoadipic acid (2-AAA) has been identified as an accurate long-term biomarker for the future development of diabetes. An investigation of over 2000 patients found that patients in the upper quartile of initial blood 2-AAA levels showed a 2-4x higher incidence of diabetes development over the...
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2011
Walker, J., Bell, R., Chan, C., Berry, T. R.
This article presents the methodology and recommendations from a consensus conference hosted in May 2011 by the Physical Activity and Nutrition for Diabetes in Alberta (PANDA) research project. The goal of the conference was to create physical activity and nutrition recommendations for people...
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Long-term Impacts of Early Life Antibiotic Exposure on Intestinal Microbiota and Metabolic Disease
DownloadFall 2015
Although genetic factors, diet choices and sedentary lifestyle have long been considered main risk contributors for obesity and diabetes mellitus, years of study show that these factors cannot fully explain the increasing rate of worldwide metabolic disease. Epidemiological studies in recent...
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Fall 2019
Cardiovascular disease (CVD) is a leading cause of morbidity and mortality worldwide. Abnormal levels of circulating lipids (dyslipidemia) is a well-known risk factor for CVD. Traditionally, fasting lipids, inclusive of low-density lipoprotein cholesterol (LDL-C) and total cholesterol (TC), have...
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Fall 2009
Islet transplantation has the potential to be an effective treatment for patients with type 1 diabetes. However, a shortage of human donor islets and the need for continuous immunosuppressive therapy currently limit this therapy to patients with brittle type 1 diabetes. Neonatal pigs may...
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Mechanisms of Pharmacists Interventions on Medication Management and Adherence in Patients with Type 2 Diabetes
DownloadSpring 2014
Optimal management of type 2 diabetes requires a collaborative, team-based approach; however, the role of pharmacists on these teams has not been well-defined. In the first study of this thesis, a systematic review examined components of pharmacist interventions to improve adherence to oral...