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Skip to Search Results- 23Graduate and Postdoctoral Studies (GPS), Faculty of
- 23Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 9Agricultural, Food and Nutritional Science, Department of
- 9Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
- 3Nursing, Faculty of
- 3School of Public Health
- 6Department of Pharmacology
- 5Centre for Neuroscience
- 4Department of Physiology
- 3Neuroscience
- 1Department of Agricultural, Food, and Nutritional Science
- 1Department of Medicine
- 2Tse, Amy (Centre for Neuroscience and Department of Pharmacology)
- 1Ballanyi, Klaus (Physiology Department, University of Alberta)
- 1Cass, Carol (Oncology)
- 1Chen, Xing-Zhen (Physiology)
- 1Clanachan, AS (Pharmacology)
- 1Clayton T. Dickson (Psychology, Physiology, Anesthesia and Pain Medicine, Neuroscience and Mental Health Institute)
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A Nutritional Perspective of Ketogenic Diet in Cancer: A Narrative Review
2018-04-01
Oliveira, Camila L. P., Mattingly, Stephanie, Schirrmacher, Ralf, Sawyer, Michael B., Fine, Eugene J., Prado, Carla M.
The predominant use of glucose anaerobically by cancer cells (Warburg effect) may be the most important characteristic the majority of these cells have in common and, therefore, a potential metabolic pathway to be targeted during cancer treatment. Because this effect relates to fuel oxidation,...
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2016
Thompson, Stephanie, Tonelli, Marcello, Klarenbach, Scott, Molzahn, Anita
Background and objectives Randomized, controlled trials show that regular exercise is beneficial for patients on hemodialysis. Intradialytic exercise may have additional benefits, such as amelioration of treatment-related symptoms. However, the factors that influence the implementation of...
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Spring 2016
This thesis examines the cellular basis of the acute (<1 hour) anti-allodynic actions of the clinically-approved neuropathic pain drug gabapentin (GBP) in rats at the level of the spinal dorsal horn and primary somatosensory cortex. Although the clinical effectiveness of the alpha-2-delta (α2δ)...
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Fall 2022
The reason and functional relevance of why we sleep continues to perplex researchers. One fundamental reason behind why sleep remains a mystery is because it is challenging to study given how easily it is disrupted. Anesthesia has been suggested to be a model for studying sleep given the...
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Antagonistic modulation of spontaneous neural network activities in isolated newborn rat brainstem preparations by opioids and methylxanthines
DownloadFall 2012
Apnea of prematurity is a common problem among the infants born before term pregnancy. Administration of respiratory stimulating drugs methylxanthines is the most frequent therapy, often in combination with the use of intubation. Opioids are used to reduce the pain associated with intubation,...
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Fall 2012
ATP actions on central inspiratory networks are determined by a three-part signaling system comprising: i) excitatory actions of ATP at P2 receptors (Rs) ii) ectonucleotidases that degrade ATP into adenosine (ADO), and iii) inhibitory actions of ADO at P1Rs. During hypoxia, an initial increase in...
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Spring 2012
Myocardial energy substrate metabolism is subjected to significant changes during ischemia and reperfusion (I/R), which can greatly influence post-ischemic recovery of left-ventricular (LV) mechanical function. One of the main mechanisms that contribute to I/R injury is the accumulation of...
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2013
Kumar Manoj, Qureshi Mosarrat J.
Background The rate of retinopathy of prematurity (ROP) in moderately premature infants has decreased dramatically with improved care in the neonatal intensive care unit. A low rate of this disorder was unexpectedly observed among infants treated with intravenous D-penicillamine to prevent...
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Fall 2014
An individual’s body weight is tightly regulated by balancing food intake with energy expenditure. This is accomplished in part by secretion of the hormone leptin by adipocytes, an excess of which signals to reduce appetite and increase activity through action in the hypothalamic region of the...