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Skip to Search Results- 1Abu-Sa'da, Omar SD
- 1Chen, Hsinyo.
- 1Panaitescu, Bogdan Alexandru
- 1Rawal, Bijal
- 1Singh, Aakanksha
- 1Waselenchuk, Quinn
- 1Ballanyi, Klaus (Department of Physiology)
- 1Ballanyi, Klaus (Physiology Department, University of Alberta)
- 1Ballanyi, Klaus (Physiology)
- 1Cheung, Po-Yin (Department of Paediatrics), Co-Supervisor
- 1Dickson, Clayton (Neuroscience and Mental Health Institute, Psychology, Physiology, Anesthesiology and Pain Medicine
- 1Funk, Gregory D (Physiology, University of Alberta)
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Fall 2022
The reason and functional relevance of why we sleep continues to perplex researchers. One fundamental reason behind why sleep remains a mystery is because it is challenging to study given how easily it is disrupted. Anesthesia has been suggested to be a model for studying sleep given the...
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Antagonistic modulation of spontaneous neural network activities in isolated newborn rat brainstem preparations by opioids and methylxanthines
DownloadFall 2012
Apnea of prematurity is a common problem among the infants born before term pregnancy. Administration of respiratory stimulating drugs methylxanthines is the most frequent therapy, often in combination with the use of intubation. Opioids are used to reduce the pain associated with intubation,...
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Fall 2012
ATP actions on central inspiratory networks are determined by a three-part signaling system comprising: i) excitatory actions of ATP at P2 receptors (Rs) ii) ectonucleotidases that degrade ATP into adenosine (ADO), and iii) inhibitory actions of ADO at P1Rs. During hypoxia, an initial increase in...
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Calcium Imaging and Field Potential Analysis of Autocrine Neuromodulation in the Locus Coeruleus of Newborn Rat Brain Slices
DownloadFall 2022
The locus coeruleus (LC) is a small brainstem nucleus that controls diverse behaviours and brain functions via release of noradrenaline (NA) in the neonatal time period. There is increasing evidence of complexity in this neuron-astrocyte ‘neural’ network that remains mostly unexplored in...
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The Effect of Caffeine on the Neurobehavioral and Neuropathological Outcome of the Newborn Rat
DownloadSpring 2010
Caffeine is used for the treatment of apnea of prematurity. The objective of this study was to determine the long term neuropathological and neurobehavioral effects of caffeine on the immature rat brain. Newborn rats were injected with either caffeine, or normal saline from postnatal days 3 to 7,...
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The Neonatal Locus Coeruleus is a Differentiated and Complex Neuromodulatory System as Revealed by Local Field Potential Analysis
DownloadSpring 2019
The locus coeruleus (LC) in the pons of the brainstem provides the sole source of noradrenergic afferent input to most brain structures including the cerebral cortex, hippocampus, cerebellum and spinal cord. The resulting modulation of activity is important for controlling behaviors like...