Search
Skip to Search Results- 1Abu-Sa'da, Omar SD
- 1Ahrari, Malema
- 1Chen, Hsinyo.
- 1Cordingley, Dean M.
- 1Elwi, Adam
- 1Froentjes, Liesbeth
-
Modulation of Spontaneous Neural Network Bursting in Newborn Rat Brain Slices by Extracellular Calcium, Methylxanthines, and Opioids
DownloadFall 2012
Spontaneous neuronal bursting appears to be pivotal for brain maturation. This thesis studied such synchronized neural network oscillations in immature newborn rat hippocampus, cortex, and locus coeruleus. For this, horizontal brain slices were generated for (simultaneous) suction electrode...
-
Nonmedical Use of Opioids Following Short Term Therapeutic Exposure in Children and Youth: A Systematic Review and Qualitative Study of Decision Maker Information Needs
DownloadFall 2021
Introduction Healthcare visits, hospitalizations, and deaths due to opioid-related harms continue to rise for children, despite an overall decline in opioid prescriptions. Decision-makers (including patients, families, clinicians, and policy-makers) require high quality syntheses to inform...
-
Fall 2019
Background: Up to 40% of patients are prescribed opioids prior to total knee arthroplasty (TKA) in the USA. These patients prescribed preoperative opioids have increased complications and worse outcomes after surgery. But, the impact of preoperative opioid use on patient-reported outcome (PRO)...
-
Fall 2009
Human cells possess multiple nucleoside transporters (NTs) that belong to either the human equilibrative or concentrative NT (hENT: hENT1/2/3/4; hCNT: CNT1/2/3) families. In the kidney, coupling of apical hCNT3 activities to basolateral hENT1/2 activities is hypothesized to mediate renal...
-
Short, Intermediate, and Long-Term Effects of Opioids on Pain Intensity in Patients with Osteoarthritis or Low Back Pain: A Systematic Review and Meta-Analysis
DownloadFall 2020
Chronic opioid use is associated with the development of hyperalgesia, which may end up attenuating any analgesic benefits over long-term therapy. We wanted to determine whether the analgesic efficacy of opioids compared to control therapy for osteoarthritis and chronic lower back pain differed...
-
Spring 2021
As one of the most accessible primary health care providers, pharmacists are in an excellent position to provide primary health care services. Although slow, the current transition from a dispensing-centered (transaction-based) pharmacy approach to a patient-centered (patient care based) approach...