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Osteosarcoma (OS) progression is associated with increased nuclear levels and transcriptional activity of Active-β-catenin (ABC)
DownloadSpring 2019
Osteosarcoma (OS) is an aggressive primary bone malignancy having peak incidence in children and young adults <25 years of age. Outcome remains poor for most patients with metastatic disease which develops in 1 of every 5 cases. However, despite the use of multimodal chemotherapeutic and surgical...
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Spring 2016
Osteosarcoma (OS) is the most common primary bone malignancy with a high incidence in children and adolescents. Current treatment strategies (surgery and adjuvant chemotherapy) has improved the overall survival rate of patients with primary OS. However, the survival rate of patients with...
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2018-01-01
Windsor Reid, Pamela J., Matveev, Eugueni, McClymont, Alexandra, Posfai, Dora, Hill, April L., Leys, Sally P.
Background: The Wnt signaling pathway is uniquely metazoan and used in many processes during development, including the formation of polarity and body axes. In sponges, one of the earliest diverging animal groups, Wnt pathway genes have diverse expression patterns in different groups including...