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Author: Lacasse, Jonathan J
Subject: Chromatin
Subject: Herpes simplex virus
Subject: Micrococcal nuclease
Departments: Department of Biochemistry
Collections: Graduate and Postdoctoral Studies (GPS), Faculty of
Collections: Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
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Fall 2010
Herpes Simplex Virus Type 1 (HSV-1) establishes latent infections in neurons in vivo and lytic infections in epithelial cells and fibroblasts. During latent infections, HSV-1 transcription is restricted and the genomes are not replicated. Latent HSV-1 genomes are chromatinized, such that...
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