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- 1Clinical trials as topic
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- 1Melatonin
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Do health care institutions value research? A mixed methods study of barriers and facilitators to methodological rigor in pediatric randomized trials.
Download2012
Scott, S. D., Hamm, M. P., Hartling, L., Klassen, T. P., Moher, D.
Background Pediatric randomized controlled trials (RCTs) are susceptible to a high risk of bias. We examined the barriers and facilitators that pediatric trialists face in the design and conduct of unbiased trials. Methods We used a mixed methods design, with semi-structured interviews building...
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Efficacy and safety of exogenous melatonin for secondary sleep disorders and sleep disorders accompanying sleep restriction: meta-analysis.
Download2006
Vandermeer, B., Hartling, L., Buscemi, N.., Baker, G., Klassen, T. P., Vohra, S., Pandya, R., Tjosvold, L., Hooton, N.
Objective To conduct a systematic review of the efficacy and safety of exogenous melatonin in managing secondary sleep disorders and sleep disorders accompanying sleep restriction, such as jet lag and shiftwork disorder. Data sources 13 electronic databases and reference lists of relevant...
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Treatment in the pediatric emergency department is evidence based: a retrospective analysis.
Download2006
Wiebe, N., Waters, K. L., Cramer, K., Klassen, T. P., Hartling, L.
Background Our goal was to quantify the evidence that is available to the physicians of a pediatric emergency department (PED) in making treatment decisions. Further, we wished to ascertain what percentage of evidence for treatment provided in the PED comes from pediatric studies. Methods We...