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Skip to Search Results- 15Agricultural, Food and Nutritional Science, Department of
- 15Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
- 3Roy Berg Kinsella Research Ranch
- 3Roy Berg Kinsella Research Ranch/Journal Articles (Kinsella Ranch)
- 1PigGen Canada
- 1PigGen Canada/Journal Articles
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Microarray analysis in caudal medulla of cattle orally challenged with bovine spongiform encephalopathy
Download2011
Williams, John L., Moore, Stephen S., Almeida, Luciane M., Basu, Urmila, Guan, Leluo
Bovine spongiform encephalopathy (BSE) is a fatal disorder in cattle characterized by progressive neurodegeneration of the central nervous system. We investigated the molecular mechanisms involved in neurodegeneration during prion infection through the identification of genes that are...
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2014
Jin, Weiwu, He, Maolong, Guan, Leluo, Romao, Josue M., McAllister, Tim
Background MicroRNAs (miRNAs) are small non-coding RNAs found to regulate several biological processes including adipogenesis. Understanding adipose tissue regulation is critical for beef cattle as fat is an important determinant of beef quality and nutrient value. This study analyzed the...
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Potential regulatory role of microRNAs in the development of bovine gastrointestinal tract during early life
Download2014
Liang, Guanxiang, Bao, Hua, Guan, Leluo, Griebel, Philip J., Stothard, Paul, McFadden, Thomas B., Malmuthuge, Nilusha
This study aimed to investigate the potential regulatory role of miRNAs in the development of gastrointestinal tract (GIT) during the early life of dairy calves. Rumen and small intestinal (mid-jejunum and ileum) tissue samples were collected from newborn (30 min after birth; n = 3), 7-day-old...
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Roles of small RNAs in the effects of nutrition on apoptosis and spermatogenesis in the adult testis
Download2015
Malecki, Irek A., Martin, Graeme B., Cozens, Greg, Hawken, Penelope A.R., Liang, Guanxiang, Guan, Yongjuan, Vercoe, Philip E., Guan, Le Luo
We tested whether reductions in spermatozoal quality induced by under-nutrition are associated with increased germ cell apoptosis and disrupted spermatogenesis, and whether these effects are mediated by small RNAs. Groups of 8 male sheep were fed for a 10% increase or 10% decrease in body mass...
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Systematic microRNAome profiling reveals the roles of microRNAs in milk protein metabolism and quality: Insights on low-quality forage utilization
Download2016
Wang, Diming, Sun, Huizeng, Liu, Jianxin, Guan, Le Luo, Wang, Bing, Liang, Guanxiang
In this study, we investigated the molecular regulatory mechanisms of milk protein production in dairy cows by studying the miRNAomes of five key metabolic tissues involved in protein synthesis and metabolism from dairy cows fed high- and low-quality diets. In total, 340, 338, 337, 330, and 328...
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Transcriptome microRNA profiling of bovine mammary epithelial cells challenged with Escherichia coli or Staphylococcus aureus bacteria reveals pathogen directed microRNA expression profiles
Download2014
Zhao, Xin, Liang, Guanxiang, Jin, Weiwu, Guan, Leluo, Beaudoin, Frédéric, Ibeagha-Awemu, Eveline M.
Background MicroRNAs (miRNAs) can post-transcriptionally regulate gene expression and have been shown to be critical regulators to the fine-tuning of epithelial immune responses. However, the role of miRNAs in bovine responses to E. coli and S. aureus, two mastitis causing pathogens, is not well...
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2011
Liao, Xiaoping, Choi, Jung-Woo, Stothard, Paul, Basu, Urmila, Sumner-Thomson, Jennifer M., Meng, Yan, Moore, Stephen S.
Background One of the goals of livestock genomics research is to identify the genetic differences responsible for variation in phenotypic traits, particularly those of economic importance. Characterizing the genetic variation in livestock species is an important step towards linking genes or...
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Whole-genome resequencing of Hanwoo (Korean cattle) and insight into regions of homozygosity
Download2013
Lee, Kyung-Tai, Ahn, Sungmin, Choy, Yun H., Lee, Sang-Heon, Jang, Gul-Won, Liao, Xiaoping, Lee, Seunghwan, Lee, Sung-Yeoun, Chung, Won-Hyong, Stothard, Paul, Choi, Jung-Woo, Kim, Tae-Hun, Kim, Bumsoo, Kim, Jiwoong, Lim, Dajeong, Moore, Stephen S., Kim, Namshin
Background Hanwoo (Korean cattle), which originated from natural crossbreeding between taurine and zebu cattle, migrated to the Korean peninsula through North China. Hanwoo were raised as draft animals until the 1970s without the introduction of foreign germplasm. Since 1979, Hanwoo has been bred...