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2015-07-31

Stothard, Paul, Liang, Guanxiang, Kommadath, Arun, Bearson, Shawn M.D., Sun, Xu, Plastow, Graham S., Bao, Hua, Guan, Le L., Tuggle, Christopher K., Arantes, Adriano S.

2016

Wang, Diming, Sun, Huizeng, Liu, Jianxin, Guan, Le Luo, Wang, Bing, Liang, Guanxiang

In this study, we investigated the molecular regulatory mechanisms of milk protein production in dairy cows by studying the miRNAomes of five key metabolic tissues involved in protein synthesis and metabolism from dairy cows fed high- and low-quality diets. In total, 340, 338, 337, 330, and 328...

2016

Janssen, Peter H., Li, Fuyong, Sun, Xu, Cox, Faith, Guan, Leluo, Henderson, Gemma

Taxonomic characterization of active gastrointestinal microbiota is essential to detect shifts in microbial communities and functions under various conditions. This study aimed to identify and quantify potentially active rumen microbiota using total RNA sequencing and to compare the outcomes of...

2015

Grebiel, Philip J., Malmuthuge, Nilusha, Guan, Leluo

A diverse microbial population colonizes the sterile mammalian gastrointestinal tract during and after the birth. There is increasing evidence that this complex microbiome plays a crucial role in the development of the mucosal immune system and influences newborn health. Microbial colonization is...

2014

Zhao, Xin, Liang, Guanxiang, Jin, Weiwu, Guan, Leluo, Beaudoin, Frédéric, Ibeagha-Awemu, Eveline M.

Background MicroRNAs (miRNAs) can post-transcriptionally regulate gene expression and have been shown to be critical regulators to the fine-tuning of epithelial immune responses. However, the role of miRNAs in bovine responses to E. coli and S. aureus, two mastitis causing pathogens, is not well...

Spring 2016

Liang, Guanxiang

Maintenance of the gut health of calves is vital because enteric infections are associated with high mortality during the pre-weaned period. The small intestine is the primary site of many enteric infections and plays an important role in protecting the host from pathogenic infection through both...

2011

Liao, Xiaoping, Choi, Jung-Woo, Stothard, Paul, Basu, Urmila, Sumner-Thomson, Jennifer M., Meng, Yan, Moore, Stephen S.

Background One of the goals of livestock genomics research is to identify the genetic differences responsible for variation in phenotypic traits, particularly those of economic importance. Characterizing the genetic variation in livestock species is an important step towards linking genes or...

2013

Lee, Kyung-Tai, Ahn, Sungmin, Choy, Yun H., Lee, Sang-Heon, Jang, Gul-Won, Liao, Xiaoping, Lee, Seunghwan, Lee, Sung-Yeoun, Chung, Won-Hyong, Stothard, Paul, Choi, Jung-Woo, Kim, Tae-Hun, Kim, Bumsoo, Kim, Jiwoong, Lim, Dajeong, Moore, Stephen S., Kim, Namshin

Background Hanwoo (Korean cattle), which originated from natural crossbreeding between taurine and zebu cattle, migrated to the Korean peninsula through North China. Hanwoo were raised as draft animals until the 1970s without the introduction of foreign germplasm. Since 1979, Hanwoo has been bred...

2015

Zhao, Xin, Pourabedin, Mohsen, Guan, Leluo

Background The emergence and spread of antibiotic resistance in pathogens have led to a restriction on the use of antibiotic growth promoters (AGPs) in animal feed in some countries. The potential negative after-effects of a ban on AGPs could be mitigated by improving animal intestinal health...