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Author: Dromparis, Peter R Subject: Mitochondria Collections: Graduate and Postdoctoral Studies (GPS), Faculty of

  • Mitochondria in Vascular Health and Disease

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    Spring 2013

    Dromparis, Peter R

    Mitochondria generate reactive oxygen species (mROS) and metabolic substrates like alpha-ketogluterate (αKG), in proportion to oxygen, which target extra-mitochondrial effectors to coordinate a cellular response. For example, acute hypoxia decreases mROS, resulting in pulmonary artery smooth...

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