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Skip to Search Results- 3Dieleman, Levinus A.
- 3Gänzle, Michael G.
- 2Baracos, Vickie E.
- 2Field, Catherine J.
- 2Ketabi, Ali
- 2Koleva, Petya
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Chemically defined diet alters the protective properties of fructo-oligosaccharides and isomalto-oligosaccharides in HLA-B27 transgenic rats
Download2014
Koleva, Petya, Ketabi, Ali, Dieleman, Levinus A., Gänzle, Michael G., Valcheva, Rosica
Non-digestible oligosaccharides (NDO) were shown to reduce inflammation in experimental colitis, but it remains unclear whether microbiota changes mediate their colitis-modulating effects. This study assessed intestinal microbiota and intestinal inflammation after feeding chemically defined...
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Inulin and fructo-oligosaccharides have divergent effects on colitis and commensal microbiota in HLA-B27 transgenic rats
Download2012-01-01
Koleva, Petya, Dieleman, Levinus, Sun, Xu, Gänzle, Michael G., Valcheva, Rosica
Modulation of intestinal microbiota by non-digestible carbohydrates may reduce inflammation in inflammatory bowel disease (IBD). The aim of the present study was to assess the effects of inulin and fructo-oligosaccharides (FOS) on intestinal microbiota and colitis in HLA-B27 transgenic rats, a...
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2012
Ketabi, Ali, Baracos, Vickie E., Field, Catherine J., Lin, Xiaoxi, Xue, Hongyu, Bibova, Ilona, Gänzle, Michael G., Dieleman, Levinus A., Sawyer, Michael B.
Intestinal microbiota mediate toxicity of irinotecan (CPT-11) cancer therapies and cause systemic infection after CPT-11-induced loss of barrier function. The intestinal microbiota and their functions are thus potential targets for treatment to mitigate CPT-11 toxicity. However, microbiota...
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Single and combined supplementation of glutamine and n-3 polyunsaturated fatty acids on host tolerance and tumour response to 7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxy-camptothecin (CPT-11)/5-fluorouracil chemotherapy in rats bearing Ward colon tumour
Download2009
Xue, Hongyu, Sawyer, Michael B., Le Roy, Severine, Dieleman, Levinus A., Baracos, Vickie E., Field, Catherine J.
Prior reports suggest that during irinotecan (7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxy-camptothecin; CPT-11) chemotherapy in laboratory rats, the anti-tumour efficacy and diarrhoea toxicity could be modulated by n-3 PUFA and glutamine, respectively. We further examined how these two...