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Skip to Search Results- 9Systematic reviews
- 5Child health
- 4Drug therapy
- 4Randomized controlled trials
- 3Clinical trials
- 3Pediatrics
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2012
Thomson, D., Chisholm, A., Hartling, L., Dryden, D. M.
Background: Overviews of systematic reviews compile data from multiple systematic reviews (SRs) and are a new method of evidence synthesis. Objectives: To describe the methodological approaches in overviews of interventions. Design: Descriptive study. Methods: We searched 4 databases from 2000 to...
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2013
Scott, S. D., Johnson, D. W., Klassen, T. P., Bishop, T., Hartling, L.
Introduction Stories may be an effective tool to communicate with patients because of their ability to engage the reader. Our objective was to evaluate the effectiveness of story booklets compared to standard information sheets for parents of children attending the emergency department (ED) with...
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2005
Klassen, T. P., Vandermeer, B., Hartling, L., Robinson, J. L., Crumley, E.
Background: Intravenous gamma globulin (IVGG) is commonly used in the management of acute myocarditis. The objective of this study was to systematically review the literature evaluating this practice. Methods: We conducted a comprehensive search (electronic databases, trials registries,...
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Acyclovir for treating varicella in otherwise healthy children and adolescents: a systematic review of randomised controlled trials.
Download2002
Wiebe, N., Klassen, T. P., Hartling, L., Belseck, E. M.
Background Acyclovir has the potential to shorten the course of chickenpox which may result in reduced costs and morbidity. We conducted a systematic review of randomised controlled trials that evaluated acyclovir for the treatment of chickenpox in otherwise healthy children. Methods MEDLINE,...
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Applying the risk of bias tool in a systematic review of combination long-acting beta-agonists and inhaled corticosteroids for persistent asthma.
Download2011
Seida, J., Vandermeer, B., Hartling, L., Dryden, D. M., Rowe, B. H., Bond, K.
Background The Risk of Bias (RoB) tool is used to assess internal validity of randomized controlled trials (RCTs). Our objectives were to: 1) evaluate inter-rater agreement of the RoB tool; 2) determine the time to access supplemental study information; 3) compare the RoB tool with the Jadad...
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2005
Klassen, T. P., Lee, D., Tubman, M., Majumdar, S. R., Friesen, C.
Recommendations for improved patients’ safety, specifically the safety of products containing potassium, are often based on practice guidelines and untested recommendations widely endorsed by various experts or organisations Valid and empirical evidence to support or discourage implementation of...
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Children are not just small adults: the urgent need for high-quality trial evidence in children.
Download2008
Offringa, M., Hartling, L., Craig, J. C., Klassen, T. P.
Children are often touted as being very important members of society because they represent our future. Optimizing their health outcomes has the potential for a huge impact on public health because children are at an early stage in the life trajectory. But it is often unclear how society...
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2005
Swingler, G., Williams, K., Hartling, L., Moyer, V., Cramer, K., Klassen, T. P., Wiebe, N.
Background The delivery of optimal medical care to children is dependent on the availability of child relevant research. Our objectives were to: i) systematically review and describe how children are handled in reviews of drug interventions published in the Cochrane Database of Systematic Reviews...
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2008
Shannahoff-Khalsa, D., Carlson, L. E., Buscemi, N., Dusek, J. A., Bond, K., Barnes, V., Ospina, M. B., Dryden, D. M., Karkhaneh, M.
OBJECTIVE: To provide a descriptive overview of the clinical trials assessing meditation practices for health care. DESIGN: Systematic review of the literature. Comprehensive searches were conducted in 17 electronic bibliographic databases through September 2005. Other sources of potentially...
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Controlled trials in children: quantity, methodological quality and descriptive characteristics of pediatric controlled trials published 1948-2006.
Download2010
Tjosvold, L., Thomson, D., Vandermeer, B., Klassen, T. P., Cohen, E., Hartling, L.
Background The objective of this study was to describe randomized controlled trials (RCTs) and controlled clinical trials (CCTs) in child health published between 1948 and 2006, in terms of quantity, methodological quality, and publication and trial characteristics. We used the Trials Register...