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Author: Bekele, Raie Taye
Subject: Chemo-resistance
Subject: Chemotherapy
Item type: Thesis
Languages: English
Collections: Graduate and Postdoctoral Studies (GPS), Faculty of
Collections: Graduate and Postdoctoral Studies (GPS), Faculty of /Theses and Dissertations
Supervisors: Brindley, David N. (University of Alberta, Biochemistry)
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Spring 2016
Tamoxifen is the accepted therapy for patients with estrogen receptor α (ERα)−positive breast cancer. However, clinical resistance to tamoxifen, as demonstrated by recurrence or progression on therapy, is frequent and precedes death from metastases. To improve breast cancer treatment it is vital...
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