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Understanding the role of diets enriched in long chain fatty acids on postpartum reproductive function and embryo development in dairy cows
DownloadSpring 2016
The objectives of this work were to investigate the influence of diets enriched in long chain fatty acids on feed intake, calf birth weight, maternal and neonatal fatty acid profiles, milk production, postpartum reproductive function, early embryonic development and its transcriptome profile in...
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Fall 2022
Endochondral ossification is a skeletal development process where mesenchymal progenitors differentiate into chondrocytes that will be eventually replaced by bone. Disrupting this process causes skeletal dysplasia. FOXC1 and FOXC2 are two transcription factors of the forkhead box family that...
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Fall 2013
PINK1 (Phosphatase Tensin homologue (PTEN)-Induced Kinase) is a neuroprotective kinase involved in mitochondrial dynamics. It is composed of an N-terminal mitochondrial targeting sequence, transmembrane domain and C-terminal kinase domain. PINK1 is imported into mitochondria and anchored into the...
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Understanding the Role of Secondary Metabolites and Endophytic Fungi in White Spruce Defenses Against Eastern Spruce Budworm
DownloadFall 2023
As a boreal tree species, white spruce (Picea glauca Moench Voss) is under a constant threat by outbreaks of defoliators (foliar feeders) including eastern spruce budworm (Choristoneura fumiferana). Historically, applications of biological insecticides and silvicultural treatments have been used...
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Spring 2013
Objectives: To explore how the concept of social capital can be utilized to generate ideas for a First Nations community oral health initiative. Methods: A qualitative case study design was employed. An interview guide developed based on Putnam’s concept of social capital directed 7 individual...
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Understanding the Role of Surface Microgeometries on Wetting: Designing Robust Superhydrophobic Surfaces
DownloadSpring 2014
This thesis is concerned with effects of surface microgeometries on wetting, aiming at providing instructions for reproducing controllable wettability on artificial surfaces and designing robust superhydrophobic surfaces. First, the origin of edge effect is understood by a thermodynamic approach...
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Understanding the Therapeutic Alliance in Young Offender Treatment through the Experiences of Male Youth
DownloadFall 2013
Therapy with youth involved in the criminal justice system presents a variety of challenges. Especially challenging is the establishment of a therapeutic alliance, which psychotherapeutic research shows is a strong predictor in the success of therapy. The purpose of this study was therefore to...
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Understanding the trans-cleavage Activity of CRISPR-Cas Systems for RNA Detection Applications
DownloadFall 2022
The discovery and characterization of Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) systems with trans-cleavage activity led to the rise of CRISPR-based diagnostics. A ribonucleoprotein (RNP), consisting of a CRISPR-associated protein (Cas) and a CRISPR RNA (crRNA) or single...