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Author / Creator / Contributor
- 1Arrieta Mendez, Marie Claire
- 1Backer, Jody Lynn
- 1Bai, Helin Daniel
- 1Déry, René
- 1Guo, Danny
- 1Lee, Thomas Wei Te
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Spring 2011
The traditional PI3K pathway relies on agonist mediated stimulation of PI3Kα through RTKs and PI3Kγ through GPCRs, which stimulate downstream enzymes such as Akt. This pathway has been found to be important in cardiomyocytes and cardiofibroblasts for regulating cardiac morphology and function....
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The role of small intestinal permeability in the pathogenesis of colitis in the interleukin-10 gene deficient mouse
DownloadSpring 2011
It is currently believed that the etiology of inflammatory bowel disease involves an aberrant immune response towards the gastrointestinal microbial flora. In addition, an increase in intestinal paracellular permeability may also be a contributing factor of disease, as it precedes disease in...
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