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Skip to Search Results- 2Molina-de-Orozco, Vivian Regina, 1955-
- 1Abou Marak Dit Roum, Darine
- 1Aguilar, Hector N
- 1Al-Momany, Abass M T
- 1Al-Zubaidy, Zaidoon A.
- 1Aljunaidy, Mais
- 5Calcium
- 4Calcium channels
- 4Pregnancy
- 3Aortic aneurysm
- 3Biological transport. Regulation.
- 3Blood-vessels. Dilatation.
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Exploratory study of egg white hydrolysate mechanisms of action in insulin sensitive tissues of high fat diet-induced insulin resistant rats
DownloadSpring 2019
Background: Chronic diseases related to the metabolic syndrome, such as type 2 diabetes and hypertension lead to complications when not treated properly. Natural approaches able to tackle multiple aspects of the metabolic syndrome and cause minimal side effects are desired. Bioactive peptides are...
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Exploring the Role of ADAM17 in Vascular Smooth Muscle Cells and Macrophages Within the Atherosclerotic Plaque
DownloadSpring 2024
Atherosclerosis, characterized by arterial fat deposits, is the root cause of many cardiovascular diseases. Plaque deposition results from a series of events initiated by elevated plasma cholesterol, inflammation of the arterial wall, cholesterol uptake, macrophage-derived foam cell formation,...
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Spring 2013
Autosomal dominant polycystic kidney disease (ADPKD) is an inherited genetic disorder, inducing cysts in kidney, liver and pancreas. It is caused by pathogenic mutations in the PKD1 or PKD2 gene encoding PKD1 or PKD2 respectively. Cellular abnormalities in ADPKD include cell over-proliferation...
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Spring 2016
Polycystin-2, encoded by the PKD2 gene, is mutated in ~15% of autosomal dominant polycystic kidney disease, and functions as a Ca2+ permeable non-selective cation channel. It is mainly localized on the endoplasmic reticulum membrane, and is also present on the plasma membrane and primary cilium....
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Function and Regulation of TRPP2 and TRPP3, and identification of pore gates of TRP channels
DownloadSpring 2017
The transient receptor potential (TRP) superfamily of cation channels is composed of eight subfamilies, TRPC/V/M/P/ML/A/N/Y, and play distinct sensory roles in response to various environmental stimuli. TRPP2, or polycystin-2, is mutated in autosomal dominant polycystic kidney disease (ADPKD)....
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Fall 2015
Polycystic kidney disease (PKD) protein 2 Like 1 (PKD2L1), also called transient receptor potential polycystin-3 (TRPP3), regulates Ca2+-dependent hedgehog signalling in primary cilia, intestinal development and sour tasting but with an unclear mechanism. PKD2L1 is a Ca2+-permeable cation channel...