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Skip to Search Results- 2Muller, Milan J.
- 1Abeywardena, Mahinda Yapa
- 1Abou-Chehade, Kassim D.
- 1Adjei, Alex Asiedu.
- 1Al-Majed, Abdulhakeem A
- 1Ali, Mohammad M. A.
- 5Rats as laboratory animals.
- 4GABA. Receptors.
- 4Metalloproteinases. Physiological effect.
- 4Pharmacology
- 3Adenosine
- 3Autophagy
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Fall 2022
The ability to reliably target specific sequences of interest is a critical component of any gene editing technology. While the discovery of CRISPR-Cas systems have fundamentally simplified the way in which genomic material may be manipulated, the presence of off-target activity at undesired loci...
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The Alberta Drug Administration Modeller (ADAM): a life-size, hands-on pharmacokinetics learning tool for our future healthcare professionals
DownloadFall 2017
The processes of absorption, distribution, metabolism, and elimination (ADME) determine a drug’s pharmacokinetics (PK). Each of these processes is described with abstract modelling, and the relationships are characterised through equations and graphical analysis using both noncompartmental and...
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The Effects of Fructose Feeding on the Quantal Catecholamine Release from Adrenal Chromaffin Cells
DownloadFall 2015
Abstract: Adrenal chromaffin cells release catecholamines in response to stress, via the exocytosis of large-dense core granules (LDCGs). Excessive stress responses, however, are harmful and can lead to the development of hypertension. The fructose-fed rats, an animal model with the symptom of...