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Skip to Search Results- 2Muller, Milan J.
- 1Abeywardena, Mahinda Yapa
- 1Abou-Chehade, Kassim D.
- 1Adjei, Alex Asiedu.
- 1Al-Majed, Abdulhakeem A
- 1Ali, Mohammad M. A.
- 5Rats as laboratory animals.
- 4GABA. Receptors.
- 4Metalloproteinases. Physiological effect.
- 4Pharmacology
- 3Adenosine
- 3Autophagy
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Spring 2016
Stress generates an adaptive behavioral and physiological response that prepares an organism for new environmental pressures. However, if stressors are perceived as uncontrollable, prolonged, or severe, they can produce exaggerated responses and result in neuropsychiatric syndromes such as...
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Spring 2019
Type 2 diabetes mellitus (T2DM) is characterized by peripheral insulin resistance and an insufficiency of insulin secretion from the pancreatic β cell. The incidence of T2DM is rising worldwide at an alarming rate. Increased prevalence of obesity is a major contributor to this rise in T2DM...
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Pain and analgesia in experimental autoimmune encephalomyelitis: Contribution of the central nucleus of the amygdala
DownloadSpring 2021
Multiple sclerosis (MS) is an autoimmune disease characterized by chronic inflammation, degeneration and demyelinating lesions within the central nervous system. Chronic pain is a highly prevalent symptom associated with MS, affecting 50-80% of patients over the course of their disease....
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Spring 2012
The common ATP-sensitive (KATP) channel variants E23K and S1369A, found in the KCNJ11 and ABCC8 genes respectively, form a haplotype that is associated with an increased risk for type 2 diabetes. Our previous studies showed that KATP channel inhibition by the A-site sulfonylurea gliclazide was...
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Pharmacological and Fluorometric Assessment of Neuronal KCNQ Channels, and Implications for Understanding Neurological Disease
DownloadSpring 2020
Epilepsy affects 60 million people worldwide, and encompasses the most common forms of neurological disorders. Epilepsy manifests in diverse ways in patients, ranging from mild cognitive effects, to seizures, to the more severe epileptic encephalopathy. While many pharmacological approaches exist...