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Skip to Search Results- 33Mass-spectrometry
- 29Chemistry
- 23Organic compounds. Synthesis.
- 22Catalysis
- 22Metabolomics
- 21Capillary electrophoresis.
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Fall 2022
The presence of arsenic in e-liquids of electronic cigarettes has rarely been studied and the few studies that have investigated the presence of arsenic have found either very low, or undetectable concentrations. Additionally, the individual species of arsenic have not been thoroughly explored...
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Synthetic and Computational Investigations into the Development of Antivirals and Viral Protein Dynamics
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Respiratory viruses are the most common cause of disease in humans, causing high death rates worldwide. Among these, respiratory syncytial virus (RSV) infection is the most significant cause of severe lower respiratory infections in children in North America and one of the leading causes of...
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Fall 2022
Throughout this thesis, methods for tailoring nanoparticles are broadly discussed and demonstrated experimentally. The main objective of this work was to help bridge the gap between fundamental materials science and global concerns by contributing to the development of functional nanomaterial...
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Fall 2022
Functionalized piperidine rings are frequently found in a variety of alkaloids and pharmaceuticals attesting to the importance of this class of heterocycles in drug discovery. According to recent data, the piperidine ring is the most abundant heterocycle found in FDA approved drugs. Thus, gaining...
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Synthesis, biological evaluation, and screening of 2,5-anhydro-D-mannitol derivatives towards selective targeting and imaging of GLUT5 transporter protein
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The solute carrier (SLC) family of membrane proteins is responsible for the internalization of a variety of essential small molecule compounds such as amino acids, monosaccharides, neurotransmitters, vitamins, as well as many inorganic ions. In recent years, these proteins have been recognized as...
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Fall 2022
The studies of [n]cumulenes have marked the 100th anniversary of Brand’s report of tetraphenylbutatriene in 1921. During the past century, hundreds of different [n]cumulenes have been studied, and [n]cumulenes are depicted as good candidates for the development of novel materials. [n]Cumulenes...
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Spring 2023
Glycosylation is one of the most abundant and diverse post-translational modifications. Glycans participate in various key biological functions and processes including immunity, cell adhesion, endocytosis, exocytosis, molecular trafficking, and signal transduction. Previous work from our lab...
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Fall 2023
Alzheimer’s disease (AD) is a common neurodegenerative dementia, and its pathological hallmarks include amyloid-β plaque and neurofibrillary tangle formation in the brain. Genome-wide association studies (GWAS) revealed that a rare single nucleotide polymorphism (SNP) in CD33 is associated with...
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Development of Chemical Isotope Labeling Liquid Chromatography Mass Spectrometry on Quadrupole-Orbitrap Mass Spectrometers for Metabolome Analysis
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Chemical isotope labeling liquid chromatography-mass spectrometry (CIL LC-MS) is a powerful technique in metabolomics, offering extensive coverage of the metabolome. This method involves dividing metabolites into sub-groups based on their functional groups and subjecting them to specific labeling...
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Multifunctional Carbazole-Based Materials as Electrochemical Water Splitting and Photoredox Catalysis
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The combustion of fossil fuels releases carbon dioxide and other harmful greenhouse gases into our living atmosphere, which traps heating and causes global warming. Renewable energy, however, can help solve the problem above by producing far fewer greenhouse gases. Renewable energy is a general...