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Skip to Search Results- 364Faculty of Pharmacy and Pharmaceutical Sciences
- 339Department of Medicine
- 117Department of Biomedical Engineering
- 14Department of Medical Sciences
- 6Department of Electrical and Computer Engineering
- 5Department of Mechanical Engineering
- 2Coulombe, Marilyne G.
- 2Kinnaird, Adam
- 2Logan, Kerry Jane, 1955-
- 2Logus, J. Wayne (John Wayne), 1951-
- 2Srivastava, Nutan
- 1AL Omair, Omar Abdulrahman
- 9Michelakis, Evangelos (Medicine)
- 9Wilman, Alan (Biomedical Engineering)
- 8Beaulieu, Christian (Biomedical Engineering)
- 8El-Kadi, Ayman (Faculty of Pharmacy and Pharmaceutical Sciences)
- 6El-Kadi, Ayman (Pharmacy and Pharmaceutical Sciences)
- 6Lavasanifar, Afsaneh (Faculty of Pharmacy and Pharmaceutical Sciences)
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Fall 2017
The voltage-gated KCNQ1/KCNE1 potassium ion channel plays a key role in maintaining the heart rhythm. An active channel generates the slow delayed rectifier (IKs) current in the heart. Both loss-of-function and gain-of-function mutations in KCNQ1 or KCNE1 are linked to many heart-related...
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A Comprehensive Dynamical Model for Human CaV1.2 Ion Channel: Structural and Functional Studies
DownloadFall 2019
Human CaV1.2 is a voltage-gated calcium channel (VGCC), which plays an essential role to maintain a normal cardiac function. Any abnormalities in CaV1.2 can lead to serious cardiac diseases (e.g. cardiac arrhythmias and Timothy syndrome). Thus, understanding the structure-function-dynamics...
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A convergence of cultures and strategies to improve Electronic Health Record implementation within a Tanzanian clinical environment
DownloadFall 2011
This research explored the question: “How can we improve the implementation of an Electronic Health Record (EHR) within a Tanzanian clinical environment?” The objectives included working with local stakeholders to identify opportunities to improve, and exploring barriers and facilitators to...
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A Discrete Choice Experiment Pilot Study: Understanding Patient Preferences for In-centre Hemodialysis
DownloadFall 2021
Background: End-stage kidney disease (ESKD) is the failure of functioning kidneys such that they no longer have the capacity to sustain life without intervention. While the incidence of ESKD has remained generally stable across all ages of Canadians since 2000, the prevalence of ESKD has been...
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Spring 2013
Aims: This study aims to 1) provide a platform to discuss and document one First Nations community’s experiences and impacts of tuberculosis (TB); and 2) to understand the social context occurring within the community which may promote continual disease transmission. Methods: This Community-Based...
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Spring 2012
In Pulmonary Arterial Hypertension (PAH), pro-constrictive, pro-proliferative and anti-apoptotic diatheses converge to produce contraction and excessive proliferation of pulmonary artery smooth muscle cells (PASMC), a hallmark of PAH-vascular remodeling. The increased afterload causes right...
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Fall 2019
Background: Global longitudinal strain (GLS) is currently a widely applied method to evaluate early left ventricular dysfunction in the oncology population. Its ability to predict left ventricular dysfunction is valid even in patients with normal ejection fraction. A significant limitation is...