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Skip to Search Results- 2Veldhoen, Richard
- 1ALSHUMAIMERI, NADA A.
- 1Acevedo Morantes, Claudia Y
- 1Aderibigbe, Ayodeji O.
- 1Ahsan, Irfan.
- 1Alabi, Adekunle
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Fall 2013
In human cells, oscillations in calcium concentration serve as a mechanism for controlling a variety of physiological processes including muscle contraction and relaxation. The sarcoplasmic reticulum (SR) is a calcium storage organelle in muscle cells that contains a calcium pump (SERCA) required...
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Fall 2012
The movement of calcium across sarcoplasmic reticulum (SR) membranes is essential in the contraction-relaxation cycle of muscle. An influx of calcium into the muscle cell from the SR triggers muscle contraction and its removal by the sarco(endo)plasmic reticulum calcium ATPase (SERCA) causes...
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Fall 2023
When calcium enters the cytosol of a muscle cell from the SR, it initiates muscle contraction, while its removal by the sarco(endo)plasmic reticulum calcium ATPase (SERCA) induces muscle relaxation. SERCA's activity is regulated by Phospholamban (PLN), which can reversibly inhibit its apparent...
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Molecular Mechanisms of the Activation of the Pattern Recognition Receptor Dectin-1 and its Induction of Immune Responses
DownloadFall 2014
In the past two decades, a rising number of fungi have emerged as serious human pathogens and the incidence of invasive fungal infections has increased enormously. Millions of people contract fungal diseases that kill at least as many people as tuberculosis or malaria, yet the global burden of...
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Molecular Mechanisms Underlying the Enhancement of Cardiac Contraction by Modifications of Troponin
DownloadFall 2015
A fine balance between contraction and relaxation is crucial for the heart to function properly. But often the heart cannot contract with enough force to meet the demands of the body. This condition, called systolic heart failure, is the leading cause of death in the modern society. A common...