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Fall 2019
Targeting a single pathway is not enough to treat cancer because of compensatory mechanisms against anticancer therapy via alternative molecular pathways for survival and proliferation of malignant cells. Given the unacceptable toxicity associated with conventional therapy, nucleic acids such as...
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Safe Polymeric Nucleic Acid Delivery Systems for Cancer Therapy: Focus on Breast Cancer and Chronic Myeloid Leukemia
DownloadFall 2021
Meenakshi Sundaram, Daniel Nisakar
RNA interference (RNAi) is a promising technology to specifically target the upregulated genes that provide uncontrolled proliferation and survival of cancers. The target specific silencing is accomplished by the delivery of small interfering RNA (siRNA), which require safe delivery systems to...
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