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Characterizing new players involved in iron homeostasis during Drosophila larval development: Shifting the classic paradigm of iron metabolism
DownloadFall 2020
Iron plays a critical role in many biological processes. The ability of iron to gain and lose electrons allows it to be involved in a wide variety of biochemical reactions. Organismal iron is commonly found in two types of protein cofactors: heme and iron-sulfur clusters (ISCs). Iron is critical...
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Characterizing novel genes involved in steroidogenesis during the larval development in Drosophila melanogaster
DownloadSpring 2022
The primary steroid hormone in Drosophila melanogaster is called ecdysone, which is synthesized in the larval prothoracic gland (PG) during developmental processes. Ecdysone biosynthesis is significantly up-regulated at the beginning of the third larval instar, resulting in a major ecdysone pulse...
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Examining whether Multicopper Oxidase 4 (Mco4) acts as a high affinity iron importer in Drosophila melanogaster
DownloadFall 2024
Iron is a crucial micronutrient for nearly all living organisms, playing a vital role in various biological processes. In humans, it is essential for the production of hemoglobin, which is necessary for oxygen transport in red blood cells. Beyond oxygen transport, iron is a key component of...
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Fall 2020
Green rust (GR) is a group of mixed FeII and FeIII hydroxide minerals and is an important phase in both modern and ancient geochemical systems. For this reason, establishing the thermodynamic properties of GR is vital to understanding and modelling its role in natural systems. In this study,...