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Chemical Synthesis to Understand and Influence Biological Systems: Spin Labels, Drug Development, and Biosynthetic Investigations
DownloadFall 2022
Spin labels are a useful tool towards the study of protein conformation and enable the mapping of interactions between specific positions within these systems. Synthetic routes towards three different chiral spin-labelled amino acids have been developed. Compared to commercially available spin...
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Spring 2023
Catalysis is essential to the modern chemical industry. Catalytic strategies can enable new synthetic methods with improved atom economy and reduced chemical waste under mild conditions, representing an indispensable approach to the development of green chemical processes with improved...
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Fall 2019
The work presented in this thesis describes the isolation of novel low-valent Group 12 and p-block element-containing molecules. Some of these molecules are shown to exhibit reactivity which mimics that of the transition metals; specifically, with respect to strong bond activation and catalysis....