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- 2Vaccine
- 1Antibodies
- 1Hepatitis C Virus
- 1Hepatitis C virus
- 1Hypervariable Region 1
- 1Isolate-Specific Neutralization
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Characterization of the Humoral Immune Response Elicited Against a Prophylactic Vaccine Composed of Recombinant Envelope Glycoproteins from Hepatitis C Virus
DownloadFall 2018
A global prophylactic vaccine for Hepatitis C Virus (HCV) remains elusive. The diversity of the virus is a major hurdle; a successful vaccine will need to protect against all 7 HCV genotypes (gt). Our lab is developing a vaccine comprising the two envelope glycoproteins of HCV (E1E2). An...
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Investigation of the Molecular Mechanisms That Determine Isolate-Specific, Antibody-Mediated Neutralization of HCV infectivity
DownloadFall 2018
It is estimated that there are about 1.75 million new Hepatitis C Virus (HCV) infections per year worldwide and around 20% will develop liver cirrhosis or liver cancer if left untreated. Direct acting antiviral drugs are available for the treatment of HCV with success rates of over 90%. But...
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