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Fall 2023
Polysialic acid (polySia) is a long homopolymer of sialic acid residues that has profound consequences for the proteins it is attached to. Its expression is restricted in healthy human adults to the nervous, reproductive, and immune systems. It contributes to neuronal development and plasticity...
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Development of methodologies to identify polysialylated proteins and to visualize receptors for polysialic acid in biological samples
DownloadFall 2024
Polysialic acid (polySia) is a homo polymer made of Sialic acid monomers linked to each other through ⍺-2-8 linkages in humans. Its expression on cellular surfaces is limited to nervous, immune, and reproductive systems in a healthy adult human. It is overexpressed in certain tumors and results...