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Fall 2021
This thesis investigates how to bolster activity dependent neuronal plasticity in conjunction with rehabilitative motor therapy to increase recovery following spinal cord injury in rats. My work focuses primarily on the injured corticospinal tract (CST) and how boosting intracellular signalling...
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Mechanism of Training Induced Functional Gains and CST Sprouting after SCI: The role of PKA Signaling
DownloadFall 2015
Currently the most effective treatment in humans for promoting recovery after spinal cord injury (SCI) is rehabilitative training. However, training is not equally effective for all injury severities and usually does not lead to complete recovery. As a result, there is a need for treatments that...