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Cryo-electron microscopy of SERCA interacting with oligomeric phospholamban and oligomeric sarcolipin
DownloadFall 2011
In 2007, heart disease was the second leading cause of death in Canadians. In heart muscle cells, calcium (Ca2+) is released from the sarcoplasmic reticulum (SR) during contraction and must be replenished for relaxation to occur. Three proteins restore Ca2+ to the SR following contraction: the...
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Synthesis and Properties of Graphyne Model Compounds and an Electrochemical Study of Substituted Pentacenes
DownloadSpring 2013
The work described in this thesis focuses on two central topics: (1) the synthesis of carbon-rich macrocycles as model compounds of the carbon allotrope graphyne and the study of their electronic properties, and (2) the electrochemical investigation of the properties of substituted pentacene...