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Skip to Search Results- 4Microparticles
- 1Advanced Drug Delivery
- 1Biomaterial
- 1Co-solvents
- 1Dispersibility enhancers
- 1Drug delivery to the lungs
- 1Choi, Hyo-Jick (Chemical and Materials Engineering)
- 1Choi, Hyo-Jick (Chemical and Materials Engineering); Soares, João.B.P. (Chemical and Materials Engineering)
- 1Finlay, Warren (Mechanical Engineering)
- 1Montemagno, Carlo (Chemical and Materials Engineering)
- 1Pepper, Andrew (Surgery)
- 1Vehring, Reinhard (Mechanical Engineering)
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Development of Oral Influenza Vaccine Delivery System Utilizing pH Responsive Pored Microparticles
DownloadFall 2015
Influenza is a major respiratory disease caused by influenza virus. Recent spread of the extremely pathogenic avian and swine influenza viruses paint a morbid picture of the emergence of a more lethal influenza virus in future. Currently, hypodermic needles are being dominantly employed in...
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Exploring New Avenues in Islet Transplantation: Localized Immune Modulations with Rapamycin-Eluting Microparticles
DownloadFall 2024
Islet transplantation (ITx) is an effective means to restore physiologic glycemic regulation in those living with type 1 diabetes; however, lifelong systemic immunosuppression required to subvert the immune response remains a major barrier to patient inclusion. While these drug therapies delay...
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Fall 2021
In this thesis, several fundamental studies were conducted to tackle some of the unanswered questions in the design and engineering of inhalable microparticles produced via spray drying. Different experimental and theoretical methods were applied to understand the mechanisms that control particle...
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Synthesis of poly(methyl methacrylate-co-methacrylic acid) copolymers and their application in the development of oral and transdermal drug delivery systems
DownloadSpring 2020
pH-responsive polymers have been intensively investigated over the years due to their diverse applications in environmental decontamination, nutrient delivery/packaging, cosmetics, and pharmaceutical science. A pH-responsive swelling/shrinkage behavior of encapsulation systems can be accounted...