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Skip to Search Results- 2Matrix Metalloproteinases
- 1Cardiomyocyte Injury
- 1Cardiopulmonary Bypass
- 1Congenital Heart Disease
- 1Doxycycline
- 1Neonate
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Matrix metalloproteinase inhibition attenuates right ventricular dysfunction and improves responses to dobutamine during acute pulmonary thromboembolism
Download2013-01-01
Neto‐Neves, Evandro M., Sousa‐Santos, Ozelia, Ferraz, Karina C., Rizzi, Elen, Ceron, Carla S., Romano, Minna M., Schulz, Richard, Tanus‐Santos, Jose E.
Activated matrix metalloproteinases (MMPs) cause cardiomyocyte injury during acute pulmonary thromboembolism (APT). However, the functional consequences of this alteration are not known. We examined whether doxycycline (a MMP inhibitor) improves right ventricle function and the cardiac responses...
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2009-01-01
Joffe, Ari R., Schulz, Christina, Rosychuk, Ronda J., Dyck, John, Rebeyka, Ivan M., Ross, David B., Cheung, Po-Yin, Schulz, Richard
During cardiopulmonary-bypass matrix-metalloproteinases released may contribute to ventricular dysfunction. This study was to determine plasma matrix-metalloproteinases in neonates after cardiopulmonary-bypass and their relation to post-operative course. A prospective observational study included...