Search
Skip to Search Results- 3DGAT
- 2Fatty Liver Disease
- 2Lipid Metabolism
- 2Saccharomyces-cerevisiae
- 2Triacylglycerol
- 1 Carnitine Palmitoyltransferase 1
- 1Ozga, Jocelyn (Department of Agricultural, Food and Nutritional Science)
- 1Tyrrell, D. Lorne (Medical Microbiology and Immunology)
- 1Weselake, Randall (Department of Agricultural, Food and Nutritional Science)
- 1Weselake, Randall J (AFNS)
- 1Weselake, Randall J (Agricultural, Food and Nutritional Science)
- 1Willing, Benjamin (Agricultural, Food, and Nutritional Science)
-
Culture and Characterization of Kefir Organisms to Reproduce the Health Benefits of Traditional Kefir
DownloadSpring 2020
Fermented dairy products such as kefir have long been associated with a host of health benefits; however, the role that microbial composition has in these benefits has not been properly examined. This research aimed to examine how kefir impacts host metabolic health, as well as how alterations to...
-
Engineering Enhanced Performance in Plant Diacylglycerol Acyltransferase and Long-Chain Acyl-CoA Synthetase
DownloadSpring 2018
Triacylglycerol (TAG) is the major storage lipid in higher plants and has great nutritional and industrial value. Plant storage lipid biosynthesis involves different subcellular compartments and a complex network of enzymes and proteins. Among them, endoplasmic reticulum (ER)-bound diacylglycerol...
-
Huh7.5 Cells Grown in Human Serum as a Model to Study the Effects of Hepatitis C Virus Infection on Lipid Catabolism
DownloadSpring 2018
Our goal is to study the additional elements of the mechanism of steatosis underlying hepatitis C virus (HCV) infection. Human hepatoma Huh7.5 cells cultured in human serum (HS) were used as a model to study the development of steatosis. Huh7.5 cells grown in HS media were chosen to study the...
-
Type-1 Brassica napus Diacylglycerol Acyltransferases: Enzyme Characterization and Molecular Tools for Increasing Storage Lipid Production in Yeast
DownloadFall 2015
Diacylglycerol acyltransferase (DGAT) catalyzes the final step in the acyl-CoA- dependent biosynthesis of triacylglycerol (TAG). The level of DGAT activity may have a substantial effect on the flow of carbon into TAG in many organisms. In plants, yeast, and animals, two families of...
-
Uncovering the Molecular Mechanisms behind Triacylglycerol Biosynthesis in Flaxseed (Linum usitatissimum L.)
DownloadFall 2015
Flax (Linum usitatissimum L.) seed oil contains approximately 45%-65% of α-linolenic acid (ALA) and 15-29 % of linoleic acid (LA), and is one of the richest natural sources of these polyunsaturated fatty acids (PUFAs). Due to its high amounts of PUFAs, especially ALA, flax oil has a number of...