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Skip to Search Results- 2Intrinsically disordered region
- 1Allosteric regulation
- 1Calcium sensitizer
- 1Cardiac troponin complex
- 1DGAT1
- 1Dilated cardiomyopathy
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Spring 2018
Diacylglycerol acyltransferase 1 (DGAT1) is an integral membrane enzyme catalyzing the final and committed step in acyl-CoA-dependent triacylglycerol (TAG) biosynthesis. Previous metabolic control analysis showed that DGAT1 plays a substantial role in modulating the flow of carbon into seed oil...
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Mutations, post-translational modifications, and small molecule binding to the cardiac troponin complex alter cardiac contractile function
DownloadFall 2021
Ischemic heart disease is the leading cause of death worldwide. It can lead to acute myocardial infarction, commonly known as a “heart attack”, in which heart muscle dies due to disruption of its oxygen and blood supply. Even if patients survive a heart attack and receive the best medical therapy...