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Murine leupaxin deletion results in spontaneous weight gain, tissue inflammation, and integrin signaling defects
DownloadFall 2020
Immune cells are remarkable in their ability to gracefully travel throughout the body to maintain homeostasis and defend against pathogens. Key proteins during immune cell migration are the integrin proteins that bind to specific ligands for robust adherence of the leukocyte to the substrate....
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Tumour-stromal interactions: Integrins and cell adhesions as modulators of mammary cell survival and transformation
Download2001
Chrenek, Micah A., Weaver, Valerie M., Wong, Paul
Stromal–epithelial interactions modulate mammary epithelial cell (MEC) growth and apoptosis by influencing cell adhesion and tissue organization. Perturbations in the mammary stroma and cell adhesion characterize breast tumors and underlie the altered tissue organization, disrupted tissue...