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- 112,13-DiHOME
- 1Cytochrome P450 epoxygenase
- 1Epoxide hydrolase
- 1Inflammation
- 1Linoleic acid
- 1Macrophage
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Fall 2023
12,13-dihydroxy-9z-octadecenoic acid (12,13-DiHOME) is a linoleic acid-derived cardiac metabolite produced in endotoxin-induced cardiomyopathy, correlating with myocardial dysfunction, inflammation, and mitochondrial damage. The contribution of 12,13-DiHOME to inflammation in the heart is...
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