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Skip to Search Results- 4Gänzle, Michael G.
- 3Finlay, B. Brett
- 3Willing, Ben P.
- 3Willing, Benjamin P.
- 2Antunes, L. Caetano M.
- 2Dieleman, Levinus A.
- 22Graduate and Postdoctoral Studies (GPS), Faculty of
- 22Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 11Agricultural, Food and Nutritional Science, Department of
- 11Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
- 2Agricultural, Life, and Environmental Sciences, Faculty of
- 2Agricultural, Life, and Environmental Sciences, Faculty of/Journal Articles (Agricultural, Life, & Environmental Sciences)
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Adherence to Clinical Care Protocols for Inflammatory Bowel Disease and Evaluation of a Clinical Decision Support System to Improve Adherence
DownloadSpring 2020
Clinical care pathways have been developed with the goal to standardize and improve quality of care. At the University of Alberta, clinical care pathways have been developed, and are currently in use, for inflammatory bowel disease patents experiencing disease flare. However, there is limited...
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2011
Willing, Benjamin P., Finlay, B. Brett , Thanachayanont, Teerawat, Croxen, Matthew, Vacharaksa, Anjalee
Host resistance to bacterial infections is thought to be dictated by host genetic factors. Infections by the natural murine enteric pathogen Citrobacter rodentium (used as a model of human enteropathogenic and enterohaemorrhagic E. coli infections) vary between mice strains, from mild...
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Campylobacter jejuni colonization is associated with a dysbiosis in the cecal microbiota of mice in the absence of prominent inflammation
Download2013
Selinger, L. Brent, Inglis, G. Douglas, Uwiera, Richard R. E., Lone, Abdul, Xu, Yong
Background Campylobacter jejuni causes enterocolitis in humans, but does not incite disease in asymptomatic carrier animals. To survive in the intestine, C. jejuni must successfully compete with the microbiota and overcome the host immune defense. Campylobacter jejuni colonization success varies...
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2017-01-06
Bording-Jorgensen, M. , O'keefe, S. , Mason, A., Warren, K., Patterson J., Jovel, J., Wong, G., Wang, W.
Multiple sclerosis (MS) is a common cause of non-traumatic neurologic disability with high incidence in many developed countries. Although the etiology of the disease remains elusive, it is thought to entail genetic and environmental causes, and microbial pathogens have also been envisioned as...
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Spring 2024
Background: The Human Microbiome is an area of increasing interest, both in and outside of the scientific community. While overall knowledge has increased exponentially, many aspects remain unclear, such as mechanisms of host-interaction and persistence. Intracellular bacteria have previously...
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Chemically defined diet alters the protective properties of fructo-oligosaccharides and isomalto-oligosaccharides in HLA-B27 transgenic rats
Download2014
Koleva, Petya, Ketabi, Ali, Dieleman, Levinus A., Gänzle, Michael G., Valcheva, Rosica
Non-digestible oligosaccharides (NDO) were shown to reduce inflammation in experimental colitis, but it remains unclear whether microbiota changes mediate their colitis-modulating effects. This study assessed intestinal microbiota and intestinal inflammation after feeding chemically defined...
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Development of ruminal and fecal microbiomes are affected by weaning but not weaning strategy in dairy calves
Download2016
Khafipour, Ehsan, Steele, Michael A., Meale, Sarah J., Plaizier, Jan C., Li, Shucong, Derakhshani, Hooman, Azevedo, Paula
The nature of weaning, considered the most stressful and significant transition experienced by dairy calves, influences the ability of a calf to adapt to the dramatic dietary shift, and thus, can influence the severity of production losses through the weaning transition. However, the effects of...
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Diet and environment shape fecal bacterial microbiota composition and enteric pathogen load of grizzly bears
Download2011-01-01
Northrup, Joseph M., Cristescu, Bogdan, Schwab, Clarissa, Stenhouse, Gordon B., Gänzle, Michael G.
Background Diet and environment impact the composition of mammalian intestinal microbiota; dietary or health disturbances trigger alterations in intestinal microbiota composition and render the host susceptible to enteric pathogens. To date no long term monitoring data exist on the fecal...
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Effect of Antimicrobial Exposure on Clostridioides difficile (C. difficile) Colonization of the Infant Gut Microbiota in the Canadian Healthy Infant Longitudinal Development (CHILD) Birth Cohort
DownloadSpring 2020
Introduction: Antimicrobial exposure in early life has been associated with gut microbiota dysbiosis and development of allergic diseases in childhood. In adults and older children, C. difficile is the major pathogen responsible for antibiotic-induced diarrhea but the effect of colonization with...
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Fall 2020
Introduction By 2030, 1/100 Canadians are predicted to be diagnosed with inflammatory bowel diseases (IBD); approximately 25% of cases are diagnosed in children. IBD include Crohn disease (CD) and ulcerative colitis (UC), and manifest with chronic gastrointestinal inflammation. Pathogenesis...