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Skip to Search Results- 4Moesin
- 2Drosophila
- 2Fruit-flies--Nervous system--Growth
- 2Immunofluorescence--Methodology
- 2Merlin
- 2Nervous system--Imaging
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Fall 2017
Merlin and the ezrin-radixin-moesin (ERM) proteins are key organizers of the cell cortex through linking membrane-associated proteins to the underlying actin cytoskeleton. Merlin and the ERM proteins have been implicated in the maintenance of cell integrity, adhesion, and motility during tissue...
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Flapwing Dephosphorylates Merlin and Moesin and Regulates Epithelial Integrity in Drosophila
DownloadFall 2013
Merlin is a tumor suppressor protein whose inactivation is associated with familial Neurofibromatosis Type II (NF2) and other sporadic tumors. The growth-suppressive function of Merlin is modulated by reversible phosphorylation. Our previous finding showed the Sterile20 kinase Slik coordinately...
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The developing fruit fly brain
2016
My research in the Hughes lab focuses on investigating the role of Moesin during nervous system development. Moesin is involved in maintaining cell integrity by linking membrane-associated proteins to the underlying actin cytoskeleton. We use fruit flies to study Moesin function as only one...
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2016-01-01
My research in the Hughes lab focuses on investigating the role of Moesin during nervous system development. Moesin is involved in maintaining cell integrity by linking membrane-associated proteins to the underlying actin cytoskeleton. We use fruit flies to study Moesin function as only one...