This decommissioned ERA site remains active temporarily to support our final migration steps to https://ualberta.scholaris.ca, ERA's new home. All new collections and items, including Spring 2025 theses, are at that site. For assistance, please contact erahelp@ualberta.ca.
Search
Skip to Search Results-
Altered ganglioside metabolism in inflammatory bowel disease and the impact of dietary ganglioside intake
DownloadFall 2014
Gangliosides are integral to the structure and function of the plasma membrane. Ganglioside composition of the small intestinal brush border membrane and apical surface of the colon influence numerous cell processes including microbial attachment, cell division, differentiation, and signaling....
-
Fall 2020
Introduction By 2030, 1/100 Canadians are predicted to be diagnosed with inflammatory bowel diseases (IBD); approximately 25% of cases are diagnosed in children. IBD include Crohn disease (CD) and ulcerative colitis (UC), and manifest with chronic gastrointestinal inflammation. Pathogenesis...
-
Fall 2013
Inflammatory bowel disease (IBD) involves chronic inflammation of all or part of the digestive tract. IBD primarily includes ulcerative colitis and Crohn disease. Gangliosides are negatively charged glycosphingolipids that consist of a hydrophobic ceramide and a hydrophilic oligosaccharide chain...
-
Fall 2021
Background A growing body of work has emerged which suggests that not only is the gut microbiome integral to maintaining human health, but also promising in the treatment of chronic inflammatory gastrointestinal diseases. Obesity and inflammatory bowel disease (IBD) are two such conditions with...
-
Isomaltodextrin dose-dependently reduces colitis development in HLA-B27 rat colitis model with associated changes to gut microbiota composition and short chain fatty acid production
DownloadFall 2021
Prevalence rates for inflammatory bowel diseases (IBD) worldwide have been drastically increasing over recent decades. IBD is characterized by altered intestinal microbiome (i.e. dysbiosis), described by reduced strict butyrate-producing anaerobes versus increased facultative anaerobes in...
-
Molecular and Epigenetic Insights into RASSF1A Regulated Pathways in Inflammatory Bowel Disease
DownloadFall 2018
Inflammatory Bowel Disease (IBD) is an idiopathic non-curable disease characterized by pain, chronic diarrhea, rectal bleeding with weight loss and erosion of the colon in severe cases. In many cases, IBD is a chronic relapsing inflammatory disorder of the gastrointestinal tract that usually...
-
Non-digestible fibers and dietary interventions: alternative approaches for the treatment of inflammatory bowel disease
DownloadSpring 2014
Crohn’s disease (CD) and ulcerative colitis (UC), collectively called inflammatory bowel disease (IBD), are associated with chronic intestinal inflammation, affecting approximately 0.7 % of Canadians. Intestinal microbial dysbiosis have been related to IBD. Therapies that manipulate gut...
-
Fall 2014
Inflammatory bowel disease (IBD) is chronic relapsing and remitting inflammation of the gastrointestinal tract resulting in abdominal pain, diarrhoea and weight loss. The two major types of IBD are Crohn’s disease (CD) and ulcerative colitis (UC). Genetic analysis has implicated several genomic...
-
Spring 2020
There is an increase in the prevalence of inflammatory bowel disease (IBD) worldwide, and this appears to be associated with an increase in the consumption of a Western diet high in fat and sugar, and low in fiber. Previous work shows that two-day exposure to high sugar diets increases the...