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Skip to Search Results- 2Macauley, Matthew S.
- 1Bubb, Abigail K.
- 1Chu, Thu
- 1Davies, Gideon J.
- 1Fajonyomi, Daniel Oluwamayowa
- 1Feldman, Mario F.
- 9Graduate and Postdoctoral Studies (GPS), Faculty of
- 9Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 3Chemistry, Department of
- 3Chemistry, Department of/Journal Articles (Chemistry)
- 1Biological Sciences, Department of
- 1Biological Sciences, Department of/R.E. Peter Biology Conference
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Spring 2021
Slow gating regulation is an extrinsic regulatory mechanism that inhibits the activation of Kv1.2 channels. Physiological factors modulating slow gating regulation are incompletely understood and the interplay between slow gating regulation and Kv1.2 channel pharmacology is unexplored. In chapter...
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2016
O’Dwyer, Michael E., Macauley, Matthew S., Natoni, Alessandro
Aberrant glycosylation is a hallmark of cancer cells with increased evidence pointing to a role in tumor progression. In particular, aberrant sialylation of glycoproteins and glycolipids has been linked to increased immune cell evasion, drug evasion, drug resistance, tumor invasiveness, and...
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Spring 2023
Glycosylation is the enzymatic modification of biomacromolecules (proteins, etc.) with carbohydrates known as glycans. Naturally occurring in all organisms from viruses to animals, glycans have multifaceted functions in all aspects of biology. Aberrant glycosylation is often observed in diseases...