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A descriptive analysis of a representative sample of pediatric randomized controlled trials published in 2007
Download2013-02-04
Hamm, Michele, Vandermeer, Ben, Thomson, Denise, Milne, Andrea, Tjosvold, Lisa, Klassen, Terry P., Curtis, Sarah, Hartling, Lisa
BACKGROUND: Randomized controlled trials (RCTs) are the gold standard for trials assessing the effects of therapeutic interventions; therefore it is important to understand how they are conducted. Our objectives were to provide an overview of a representative sample of pediatric RCTs published in...
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A Discrete Choice Experiment Pilot Study: Understanding Patient Preferences for In-centre Hemodialysis
DownloadFall 2021
Background: End-stage kidney disease (ESKD) is the failure of functioning kidneys such that they no longer have the capacity to sustain life without intervention. While the incidence of ESKD has remained generally stable across all ages of Canadians since 2000, the prevalence of ESKD has been...
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A Nutritional Perspective of Ketogenic Diet in Cancer: A Narrative Review
2018-04-01
Oliveira, Camila L. P., Mattingly, Stephanie, Schirrmacher, Ralf, Sawyer, Michael B., Fine, Eugene J., Prado, Carla M.
The predominant use of glucose anaerobically by cancer cells (Warburg effect) may be the most important characteristic the majority of these cells have in common and, therefore, a potential metabolic pathway to be targeted during cancer treatment. Because this effect relates to fuel oxidation,...
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2016
Thompson, Stephanie, Tonelli, Marcello, Klarenbach, Scott, Molzahn, Anita
Background and objectives Randomized, controlled trials show that regular exercise is beneficial for patients on hemodialysis. Intradialytic exercise may have additional benefits, such as amelioration of treatment-related symptoms. However, the factors that influence the implementation of...
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Fall 2016
End-stage renal disease (ESRD) requiring hemodialysis (HD) is associated with poor health outcomes including low quality of life and physical functioning. The association between quality of life (QoL), mortality and hospitalization is well established; however, few interventions have been shown...