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Skip to Search Results- 1Abd Elhafiz, Areeg
- 1Abeysundara, Namal W
- 1Anderson-Baron, Matthew N
- 1Androschuk, Alaura MA
- 1Arnold, Kirsten J
- 1Ayeni, Joseph O
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The Study of Hereditary Spastic Paraplegia Genes Using Drosophila Homologues: Behavioural Insights
DownloadFall 2014
Hereditary Spastic Paraplegia (HSP) denotes a heterogeneous group of heritable neurodegenerative disorders predominantly characterized by progressive weakness and spasticity of the legs. Mutations in the gene SPAST are by far the most common, while mutations in the gene ATL1 are the second most...
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The roles of vestigial and scalloped in the embryonic muscle development of Drosophila melanogaster
DownloadFall 2010
Vertebrate development requires the activity of multiple members of the myocyte enhancer factor 2 (mef2) gene family for muscle cell specification and subsequent differentiation. Additionally, it is thought that several muscle-specific functions of MEF2 family proteins require binding additional...
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Fall 2014
Fragile X Syndrome (FXS) is the most common genetic cause of Intellectual Disability, affecting 1 in 4000 boys and 1 in 6000 girls. Work in our lab using Drosophila melanogaster and since replicated in the mouse model has shown that excess protein synthesis is a major mechanism connecting the...