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Skip to Search Results- 6Lewis, Mark A.
- 3Evenden, Maya L.
- 2Cooke, Janice E. K.
- 2Goodsman, Devin W.
- 2Gänzle, Michael G.
- 2Jones, Kelsey L.
- 26Biological Sciences, Department of
- 25Graduate and Postdoctoral Studies (GPS), Faculty of
- 25Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 24Biological Sciences, Department of/Journal Articles (Biological Sciences)
- 9The NSERC TRIA Network (TRIA-Net)
- 9The NSERC TRIA Network (TRIA-Net)/Journal Articles (TRIA-Net)
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Spring 2010
More than 90% of human genes undergo a processing step called splicing, whereby non-coding introns are removed from initial transcripts and coding exons are ligated together to yield mature messenger RNA. Roughly 50% of human genetic diseases correspond to aberrant splicing. Splicing is...
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Fall 2012
Thuricin CD, a two-component bacteriocin produced by Bacillus thuringiensis DPC 6431, exhibits potent activity against the hospital superbug Clostridium difficile ribotype O27. The two peptides (Trn-α and Trn-β) that constitute thuricin CD operate synergistically to kill sensitive bacteria at...
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Structure and dynamics of biomolecules: probing muscle regulation, prion protein unfolding, and drug insertion into DNA by nuclear magnetic resonance spectroscopy
DownloadSpring 2011
Nuclear magnetic resonance (NMR) spectroscopy is a powerful approach to study the structure and dynamics of macromolecules in a close-to-native solution environment. In the present thesis I present my investigation of protein and nucleic acid structure and dynamics in a wide variety of biological...
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Fall 2019
The Himalayan orogen is segmented along its strike at the scale of hundreds of kilometres. This segmentation is apparent from along-strike changes in earthquake rupture patterns, thickness changes, deformation styles, topographic gradients, thermal evolution, and faults at oblique angles to the...
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Testing for trade-offs between flight and reproduction in the mountain pine beetle (Coleoptera: Curculionidae) on two pine hosts
Download2019-01-01
Wijerathna, Asha, Whitehouse, Caroline, Proctor, Heather, Evenden, Maya
Mountain pine beetle, Dendroctonus ponderosae Hopkins (Coleoptera: Curculionidae: Scolytinae) adults fly to disperse before host colonization. The effect of flight on reproduction was tested by comparing the number and quality of offspring from beetles flown on flight mills to that of unflown...
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The genetic signature of rapid range expansions: How dispersal, growth and invasion speed impact heterozygosity and allele surfing
Download2014-01-01
Lewis, Mark A. , Coltman, David W. , Goodsman, Devin W., Cooke, Barry
As researchers collect spatiotemporal population and genetic data in tandem, models that connect demography and dispersal to genetics are increasingly relevant. The dominant spatiotemporal model of invasion genetics is the stepping-stone model which represents a gradual range expansion in which...
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The mating system, dispersal behavior and genetic structure of a collared pika (Ochotona collaris: Ochotonidae) population in the southwest Yukon, and a phylogeny of the genus Ochotona.
DownloadFall 2011
Pikas (Ochotona, Ochotonidae) are small, short-eared lagomorphs that inhabit steppes and mountains in northern and central Asia and alpine regions in western North America. I examined the dispersal patterns, genetic structure and mating system of a collared pika (O. collaris) population from the...
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2016-01-01
Goodsman, Devin W., Lewis, Mark A.
Dispersal can push population density below strong Allee thresholds ensuring the demise of small founding populations. As a result, for isolated populations of dispersing organisms, the minimum founding population size that enables establishment can be quite different from the Allee threshold. 2....
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Fall 2011
Recent shifts towards spatial issues within education are examined, and mapping is identified as particularly important. The multidisciplinary trend of complexity science is surveyed, in turn, through the lens of physics and education research. The provincial education system of Alberta is...