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Skip to Search Results- 8University of Alberta, Department of Biological Sciences
- 5Wang, J.
- 3Kitova, Elena N.
- 3Klassen, John S.
- 3Li, S.
- 3Sun, Jiangxiao
- 43Graduate and Postdoctoral Studies (GPS), Faculty of
- 43Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 22Biological Sciences, Department of
- 14Biological Sciences, Department of/Journal Articles (Biological Sciences)
- 8Biological Sciences, Department of/BioSci OER
- 4Chemistry, Department of
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The mitochondrial genome of the hexactinellid sponge Aphrocallistes vastus: Evidence for programmed translational frameshifting
Download2008
Rosengarten, R.D., Sperling, E.A., Leys, S.P., Dellaporta, S.L., Moreno, M.A.
Background: Mitochondrial genomes (mtDNA) of numerous sponges have been sequenced as part of an ongoing effort to resolve the class-level phylogeny of the Porifera, as well as to place the various lower metazoan groups on the animal-kingdom tree. Most recently, the partial mtDNA of two glass...
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Spring 2024
DNA double-strand breaks (DSBs) are considered the most deleterious DNA lesions. Unrepaired or incorrectly repaired DSBs can lead to cell cycle arrest, apoptosis, or over time, the accumulation of mutations and chromosomal abnormalities that give rise to cancer. The repair of DSBs by homologous...
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The roles of vestigial and scalloped in the embryonic muscle development of Drosophila melanogaster
DownloadFall 2010
Vertebrate development requires the activity of multiple members of the myocyte enhancer factor 2 (mef2) gene family for muscle cell specification and subsequent differentiation. Additionally, it is thought that several muscle-specific functions of MEF2 family proteins require binding additional...
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The Study of Hereditary Spastic Paraplegia Genes Using Drosophila Homologues: Behavioural Insights
DownloadFall 2014
Hereditary Spastic Paraplegia (HSP) denotes a heterogeneous group of heritable neurodegenerative disorders predominantly characterized by progressive weakness and spasticity of the legs. Mutations in the gene SPAST are by far the most common, while mutations in the gene ATL1 are the second most...
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Fall 2014
Developing a simple, general, and isothermal self-replicating system is one of the key requirements for a simplified detection platform for nucleic acid sequences specific to a disease causing microrganism. One of the challenges in achieving nucleic-acid templated isothermal amplification is that...
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Fall 2014
Fragile X Syndrome (FXS) is the most common genetic cause of Intellectual Disability, affecting 1 in 4000 boys and 1 in 6000 girls. Work in our lab using Drosophila melanogaster and since replicated in the mouse model has shown that excess protein synthesis is a major mechanism connecting the...
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Using Biomolecular Recognition to Selectively Self-Assemble Microscale Components onto Patterned Substrates
DownloadSpring 2015
Modern nanofabrication technology in the 21st century has continued year after year to push the boundaries of what is possible at the nanoscale. With the advent of molecular electronics, single electron devices, nanoelectromechanical systems (NEMS), and other nanotechnologies, the near future...