This decommissioned ERA site remains active temporarily to support our final migration steps to https://ualberta.scholaris.ca, ERA's new home. All new collections and items, including Spring 2025 theses, are at that site. For assistance, please contact erahelp@ualberta.ca.
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Site-directed mutagenesis of charged amino acid residues on the CpxASD and CpxP in E. coli, potentially important for signaling and direct interaction
DownloadSpring 2019
Bacterial pathogens must endure diverse environmental stresses that they encounter while colonizing and infecting a host. Two-component signal transduction systems (TCSTs) are the most widespread regulatory systems in bacteria, but importantly absent in mammals. In general, TCSTs sense and...
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The Cpx and Rcs responses signal envelope stress through independent mechanisms but are coordinated through the RprA sRNA in the cytoplasm
DownloadFall 2018
Bacteria have several mechanisms which play a major role in adaptation to environmental stresses. One method involves the use of signal sensing pathways that activate transcription of specific genes encoding proteins to alleviate bacterial stress. Upon sensing an inducing cue, an inner...
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Spring 2018
The fitness and survival of bacteria depends on their ability to adapt and survive in different ecological niches during its life cycle. Bacteria must therefore be able to sense the different changes in the environment during the transition between different ecological niches to enhance survival....
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The role of cysteine and the Cpx envelope stress response in alleviating zinc induced stress in Escherichia coli
DownloadFall 2018
Circumscribing the interior of Gram negative bacteria are two sets of layers: an inner and outer membrane. The periplasm and murein occupy the space between these membranes and acts as a site for protein folding and degradation. The bacterial envelope, as a whole, plays an essential role in the...