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Skip to Search Results- 1Abdualmjid,Reem J
- 1Bahitham, Wesam Ahmad
- 1Baracos, Vickie E.
- 1Bekaii-Saab, Tanios
- 1Doyle, L. Austin
- 1Ghosh, Sunita
- 2Graduate and Postdoctoral Studies (GPS), Faculty of
- 2Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 1Agricultural, Food and Nutritional Science, Department of
- 1Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
- 1Bamforth, Fiona (Co-supervisor, Department of Laboratory Medicine & Pathology)
- 1Bamforth, Fiona (Department of Laboratory Medicine and Pathology)
- 1Sergi, Consolato (Department of Laboratory Medicine and Pathology and Department of Pediatrics)
- 1Sergi, Consolato (Supervisor, Department of Laboratory Medicine & Pathology)
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Mitochondrial Dysfunction and Induction of Apoptosis in Hepatocellular Carcinoma and Cholangiocarcinoma Cell Lines by Thymoquinone
DownloadSpring 2015
Thymoquinone, the plant-based bioactive constituent derived from the volatile oil of Nigella sativa, has been shown to possess considerable anti-neoplastic activity. The present study aimed to investigate the anti-tumour property of TQ against hepatocellular carcinoma (HepG2) and...
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Spring 2013
Cholangiocellular carcinoma (CCA) is the second most common hepatic malignancy, but its carcinogenesis is poorly understood. Somatic mitochondrial DNA (mtDNA) mutations have been demonstrated in a variety of human cancers. However, no study has previously investigated mitochondria and their...
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Skeletal muscle anabolism is a side effect of therapy with the MEK inhibitor: Selumetinib in patients with cholangiocarcinoma
Download2012
Ghosh, Sunita, Doyle, L. Austin, Baracos, Vickie E., Prado, Carla M., Sawyer, Michael B., Bekaii-Saab, Tanios, Shrestha, Suraj
background: Cancer cachexia is characterised by skeletal muscle wasting; however, potential for muscle anabolism in patients with advanced cancer is unproven. methods: Quantitative analysis of computed tomography images for loss/gain of muscle in cholangiocarcinoma patients receiving selumetinib...