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Skip to Search Results- 31Graduate and Postdoctoral Studies (GPS), Faculty of
- 31Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
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B cell Tolerance Mechanisms Following ABO-incompatible Infant Heart Transplant: A Potential Role for CD22
DownloadSpring 2015
Due to presumed immune immaturity, infants are able to accept heart transplants across the ABO barrier, a procedure that would result in catastrophic consequences if performed in adults. Our group has demonstrated that following ABO-incompatible heart transplantation (ABOi HTx), infants develop...
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2014
Mager, Diana R., Chan, Catherine B., Ambler, Kathryn, Salawi, Hebah, Padwal, Rajdeep S., Ball, Geoff D. C.
Background Severe obesity (SO) in pediatrics has become increasing prevalent in recent decades. The objective of our study was to examine differences in demographic, anthropometric, cardiometabolic, and lifestyle variables in children and youth with SO versus their less overweight/obese (OW/OB)...
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Children are not just small adults: the urgent need for high-quality trial evidence in children.
Download2008
Offringa, M., Hartling, L., Craig, J. C., Klassen, T. P.
Children are often touted as being very important members of society because they represent our future. Optimizing their health outcomes has the potential for a huge impact on public health because children are at an early stage in the life trajectory. But it is often unclear how society...
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2005
Swingler, G., Williams, K., Hartling, L., Moyer, V., Cramer, K., Klassen, T. P., Wiebe, N.
Background The delivery of optimal medical care to children is dependent on the availability of child relevant research. Our objectives were to: i) systematically review and describe how children are handled in reviews of drug interventions published in the Cochrane Database of Systematic Reviews...
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Fall 2015
There is a concern that brain tumours are underreported in the Alberta Cancer Registry (ACR), yet no studies have been performed to investigate this issue. This study addresses the concern of underreporting of brain tumours in the ACR by assessing case ascertainment of primary brain tumours cases...
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Spring 2015
Introduction Systematic reviews (SRs) synthesize published and sometimes unpublished data and are often based on randomized controlled trials (RCTs). However, RCTs are known to be poor at identifying and reporting harms. The PRISMA (Preferred Reporting Items for Systematic Reviews and...
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Content Validity of a Questionnaire Specifically Designed to Clinically Identify Pediatric Environmental Exposures
DownloadSpring 2014
Various clinical questionnaires exist to assist clinicians with the diagnosis, prognosis, long-term follow up of a disease, or even to assess quality of life. However, any questionnaire must be evaluated for its validity and reliability before application. Invalid or unreliable questionnaires can...
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Controlled trials in children: quantity, methodological quality and descriptive characteristics of pediatric controlled trials published 1948-2006.
Download2010
Tjosvold, L., Thomson, D., Vandermeer, B., Klassen, T. P., Cohen, E., Hartling, L.
Background The objective of this study was to describe randomized controlled trials (RCTs) and controlled clinical trials (CCTs) in child health published between 1948 and 2006, in terms of quantity, methodological quality, and publication and trial characteristics. We used the Trials Register...
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2012
Small, S.P., Neufeld, A., Kushner, K.E.
The purpose of this study was to understand parental approach to the topic of smoking with school-age preadolescent children. In-depth interviews were conducted with 38 parents and yielded a grounded theory that explains how parents communicated with their children about smoking. Parents...
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Developing a Patient-Driven Arts-Based Knowledge Translation Tool for Parents of Children with Asthma
DownloadSpring 2016
Background: Family-centered education is critical to managing childhood asthma, the most common chronic disease of childhood in North America. Parents are largely responsible for the day-to-day management of their child’s asthma; as such, finding effective ways to educate parents about asthma is...