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Skip to Search Results- 1Abu Alrub, Osama Y
- 1Ahrari, Malema
- 1Avis, Jillian LS
- 1Bahry, Ashley MA.
- 1Corrigan, Jennifer
- 1Dhaliwal, Khushmol K.
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Alterations in Neural Connectivity following Placental Insufficiency, its Role in Neurodevelopmental Disabilities, and the Neuropreventive Effects of Broccoli Sprout Supplementation: A Potential Therapeutic Intervention
DownloadFall 2017
Background Intrauterine growth restriction (IUGR) as a result of suboptimal in utero environments can cause perinatal brain injury and ultimately lead to neurodevelopmental disorders (NDD). In the developed world placental insufficiency (PI) is the leading cause of IUGR. This antepartum insult...
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Appetite-Regulating Hormones and Eating Behaviors in Children with Autism Spectrum Disorder
DownloadFall 2020
Autism Spectrum Disorder (ASD) is a complex neurodevelopmental disorder that involves deficits in social, behavioral, and communicative domains. As an increasing number of children are diagnosed with ASD, within Canada and globally, there has also been increased findings of higher rates of...
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Bilateral Uterine Artery Ligation in Rats cultivates Long Term Neurological Deficits reminiscent of Human Cerebral Palsy: A model for Therapeutic Intervention.
DownloadFall 2015
Introduction Cerebral Palsy (CP) is a ubiquitous term used to describe a group of permanent, non-progressive disorders of movement, posture, and behaviour. Despite countless advances in neonatal medicine, the incidence of CP has remained constant in term infants over the last three decades. More...
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Development of Conversation Cards for Adolescents©: A patient-centered communication and behavior change tool for adolescents with obesity and health care providers
DownloadFall 2019
Background. Given adolescents’ increasing desire for independence and autonomy, there is a need for research to examine their lived experiences, including concerns, preferences, and priorities. In the context of lifestyle modification for weight management, most adolescents with obesity exhibit...
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Enrollment in Multidisciplinary Clinical Care for Pediatric Weight Management: Predictors, Reasons, Facilitators, and Recommendations
DownloadFall 2017
Background: One-third of Canadian children meet the criteria for overweight or obesity. While multidisciplinary clinical care (MCC) can be effective to manage pediatric obesity, many eligible children are not referred to this level of care and many of those who are referred do not enroll in...
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Hypothermia and the Evaluation of Combination Therapies for Neonatal Hypoxic-Ischemic Brain Damage
DownloadFall 2016
Hypoxic-ischemic brain damage (HIBD) is still of major concern in the neonatal period, resulting in chronic neurological sequelae stemming from damage to the term newborn brain. Full-body and focal-head cooling within 6 hours of birth have proven neuroprotective in human newborns and various...
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Investigating the Role of In Utero Inflammation on Neurodevelopment in the Fetus and Offspring and the Neuroprotective Properties Afforded by Broccoli Sprouts
DownloadFall 2016
Introduction Maternal infection and inflammation leading to a fetal inflammatory response (FIR) is a risk factor for perinatal brain damage. Perinatal brain injury can lead to neurodevelopmental disorders, the sine quo non outcome parameter of which is cerebral palsy (CP). Despite advances in...
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Spring 2016
Cerebral Palsy (CP) constitutes the primary outcome of premature nerve injury. Impairment of oxygen and glucose supply during pregnancy to the fetus can induce neuron damage and death. Mental retardation, seizures, learning disabilities, and other mental diseases can occur as a result of this...
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Nonmedical Use of Opioids Following Short Term Therapeutic Exposure in Children and Youth: A Systematic Review and Qualitative Study of Decision Maker Information Needs
DownloadFall 2021
Introduction Healthcare visits, hospitalizations, and deaths due to opioid-related harms continue to rise for children, despite an overall decline in opioid prescriptions. Decision-makers (including patients, families, clinicians, and policy-makers) require high quality syntheses to inform...
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Fall 2014
Cardiac Fatty acids β-oxidation (FAO) markedly increases during maturation and become the major source of energy for the adult heart. However, excessive rates of FAO can compromise cardiac function in obesity, diabetes, and heart failure. Lysine acetylation has recently been identified as a...